KRT18 and TUBGCP4

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KRT18	TUBGCP4
Description		keratin 18	tubulin gamma complex component 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Microtubule Organizing Center Cytosol Cytoskeleton Intermediate Filament Adherens Junction Nuclear Matrix Centriolar Satellite Keratin Filament Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery	Spindle Pole Gamma-tubulin Complex Gamma-tubulin Ring Complex Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Microtubule Cytoskeleton Membrane Recycling Endosome
	Molecular Function	RNA Binding Structural Molecule Activity Protein Binding Scaffold Protein Binding Cadherin Binding Involved In Cell-cell Adhesion	Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	Anatomical Structure Morphogenesis Tumor Necrosis Factor-mediated Signaling Pathway Golgi To Plasma Membrane Protein Transport Negative Regulation Of Apoptotic Process Intermediate Filament Cytoskeleton Organization Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process Cell-cell Adhesion	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly
Pathways		Keratinization Formation of the cornified envelope Developmental Lineage of Mammary Gland Luminal Epithelial Cells Developmental Lineage of Mammary Gland Alveolar Cells	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Diffusing capacity of carbon monoxide ( 30694715) Nonsyndromic cleft lip with cleft palate ( 28232668)	Glycine levels ( 30837465) HDL cholesterol ( 30275531) Liver enzyme levels (alkaline phosphatase) ( 33972514) Triglycerides ( 30275531)
Interacting Genes		94 interacting genes: AIRIM BBS1 BBS2 BBS4 BBS7 CAMK2A CASP3 CASP6 CASP7 CASP8 CBL CCDC146 CCDC85B CCHCR1 CCNI CDC5L CDK1 COL17A1 DEDD DNAJB6 EFHC1 EGFR EP300 ESR1 EXOC8 FRAT1 FXR1 FXR2 GIT2 GOLGA2 GRN HAUS1 HGS HRAS HSPA1A HSPA4 HSPA5 HSPB1 IKBKG KIFC3 KPNA2 KRT15 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT8 KRT81 LDOC1 LINC01554 MAPK14 NEFL NME7 ORC5 PDE4B PDE4DIP PIAS4 PKD1 PKP2 PKP3 PNN POT1 PRKCA PRKCE PSTPIP2 RAF1 RCOR3 RHPN2 RPS6KA3 SERPINE1 SHC1 SMARCD1 SVIL SYCE1 TCHP TEKT4 TNFRSF1B TRADD TSG101 TUBG1 TUBGCP4 TXN2 TXNDC11 UPF2 USH2A WBP2 YTHDC1 YWHAB YWHAE YWHAG YWHAH YWHAZ	32 interacting genes: ADAMTSL4 AP2B1 CBY2 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 FDXACB1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 KRT4 KRT6B LZTR1 MAD1L1 NUDT3 PAK5 PHKA1 RNF146 RPRD1B SDSL STN1 TRIM27 TRIM55 TRIM63 TUBG1 USHBP1 VIM
Entrez ID		3875	27229
HPRD ID		01020	10616
Ensembl ID		ENSG00000111057	ENSG00000137822
Uniprot IDs		P05783	Q9UGJ1
PDB IDs			3RIP 6V69 6V6S 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 7QJE 8Q62 8RX1 8VRD 8VRJ 8VRK
Enriched GO Terms of Interacting Partners?		Cytosol Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Cytoplasm Organelle Organization Cytoskeleton Organization Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Cytoskeleton Establishment Of Protein Localization Nucleus Developmental Process Supramolecular Fiber Organization BBSome Regulation Of Apoptotic Process Intracellular Protein Localization Protein Domain Specific Binding Regulation Of Programmed Cell Death Cellular Component Assembly Centrosome Regulation Of Protein Metabolic Process Keratinization Establishment Of Localization In Cell Reproductive Process Response To Lipid Enzyme Binding Apoptotic Process Protein Binding Regulation Of Cellular Component Organization Programmed Cell Death Cell Death Cellular Response To Staurosporine Ciliary Basal Body Cellular Localization Negative Regulation Of Programmed Cell Death Apoptotic Signaling Pathway Regulation Of Protein Localization Intracellular Signal Transduction Hippocampus Development Regulation Of Microtubule Nucleation Phosphoserine Residue Binding Focal Adhesion Pyroptotic Inflammatory Response Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Apoptotic Process Regulation Of Macromolecule Biosynthetic Process Death-inducing Signaling Complex Desmosome Assembly	Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Cytoskeleton Intermediate Filament Organization Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Cytoskeleton Organization Supramolecular Fiber Organization Cytoskeleton Identical Protein Binding Bergmann Glial Cell Differentiation Structural Constituent Of Skin Epidermis Scaffold Protein Binding Microtubule Astrocyte Development
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