STRN4 and KLHDC2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		STRN4	KLHDC2
Gene Name		striatin, calmodulin binding protein 4	kelch domain containing 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Cytoplasm Membrane Dendritic Spine	Nucleus
	Molecular Function	Protein Binding Calmodulin Binding Protein Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Biological_process
Pathways
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 18758461)
Protein-Protein Interactions		22 interactors: AK5 ASNS CALM1 CAV1 CLDN12 DDX39B DFFA ECSIT GDF9 JUN KLHDC2 LPPR3 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PPBP SLC25A6 WIPI2 WNT7A	2 interactors: EZH2 STRN4
Entrez ID		29888	23588
HPRD ID		18125	08824
Ensembl ID		ENSG00000090372	ENSG00000165516
Uniprot IDs		F5GYK2 F8VYA6 Q59GV6 Q9NRL3	Q9Y2U9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Autophosphorylation Cellular Response To Starvation Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Regulation Of Oxidoreductase Activity Negative Regulation Of Protein Autophosphorylation Positive Regulation Of Phosphorylation Regulation Of Phosphorylation Response To External Stimulus Response To Organic Cyclic Compound Cellular Localization Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Regulation Of Apoptotic Process Response To Calcium Ion Regulation Of Phosphorus Metabolic Process Regulation Of Cell Death Regulation Of Protein Phosphorylation Response To Wounding Positive Regulation Of Protein Phosphorylation Nitric Oxide Metabolic Process Mitochondrion Organization Reactive Nitrogen Species Metabolic Process Response To Nutrient Levels Regulation Of Nitric-oxide Synthase Activity Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Immune System Process Response To Extracellular Stimulus Response To Lipid Response To Transforming Growth Factor Beta Response To Organic Substance Positive Regulation Of Ion Transport Cell Communication Positive Regulation Of Cellular Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Ion Transmembrane Transport Regulation Of Cell Cycle Establishment Of Localization In Cell Regulation Of Membrane Repolarization During Action Potential Positive Regulation Of Prostaglandin Secretion Involved In Immune Response DADP Biosynthetic Process Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Wnt Signaling Pathway Involved In Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Apoptotic DNA Fragmentation Cellular Response To Potassium Ion Starvation L-asparagine Biosynthetic Process	Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration G1 To G0 Transition Negative Regulation Of Epidermal Cell Differentiation Histone H3-K27 Methylation Protein Localization To Chromatin Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Striated Muscle Cell Differentiation Skeletal Muscle Tissue Regeneration Protein Localization To Chromosome Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Epithelial Cell Differentiation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Muscle Cell Differentiation Regulation Of Epidermal Cell Differentiation Regulation Of Retinoic Acid Receptor Signaling Pathway Tissue Regeneration Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Stem Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Cellular Response To Hydrogen Peroxide DNA Methylation Cerebellar Cortex Development Regulation Of Epidermis Development Negative Regulation Of Gene Expression, Epigenetic DNA Modification Histone Lysine Methylation Peptidyl-lysine Methylation Regulation Of Circadian Rhythm Regulation Of Striated Muscle Cell Differentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Reactive Oxygen Species Regulation Of Gliogenesis
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