STRN4 and DFFA

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		STRN4	DFFA
Gene Name		striatin, calmodulin binding protein 4	DNA fragmentation factor, 45kDa, alpha polypeptide
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Cytoplasm Membrane Dendritic Spine	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Lipid Particle Cytosol
	Molecular Function	Protein Binding Calmodulin Binding Protein Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding	Protein Binding
	Biological Process	Biological_process	Apoptotic DNA Fragmentation Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Positive Regulation Of Apoptotic Process Thymocyte Apoptotic Process Negative Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Apoptotic DNA Fragmentation
Pathways			Activation of DNA fragmentation factor Apoptosis induced DNA fragmentation Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 18758461)
Protein-Protein Interactions		22 interactors: AK5 ASNS CALM1 CAV1 CLDN12 DDX39B DFFA ECSIT GDF9 JUN KLHDC2 LPPR3 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PPBP SLC25A6 WIPI2 WNT7A	11 interactors: CASP3 CASP7 CIDEB DFFB EWSR1 GZMB GZMM NECAB2 STRN4 YWHAG YWHAZ
Entrez ID		29888	1676
HPRD ID		18125	03531
Ensembl ID		ENSG00000090372
Uniprot IDs		F5GYK2 F8VYA6 Q59GV6 Q9NRL3	O00273
PDB IDs			1IBX 1IYR 1KOY
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Autophosphorylation Cellular Response To Starvation Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Regulation Of Oxidoreductase Activity Negative Regulation Of Protein Autophosphorylation Positive Regulation Of Phosphorylation Regulation Of Phosphorylation Response To External Stimulus Response To Organic Cyclic Compound Cellular Localization Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Regulation Of Apoptotic Process Response To Calcium Ion Regulation Of Phosphorus Metabolic Process Regulation Of Cell Death Regulation Of Protein Phosphorylation Response To Wounding Positive Regulation Of Protein Phosphorylation Nitric Oxide Metabolic Process Mitochondrion Organization Reactive Nitrogen Species Metabolic Process Response To Nutrient Levels Regulation Of Nitric-oxide Synthase Activity Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Immune System Process Response To Extracellular Stimulus Response To Lipid Response To Transforming Growth Factor Beta Response To Organic Substance Positive Regulation Of Ion Transport Cell Communication Positive Regulation Of Cellular Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Ion Transmembrane Transport Regulation Of Cell Cycle Establishment Of Localization In Cell Regulation Of Membrane Repolarization During Action Potential Positive Regulation Of Prostaglandin Secretion Involved In Immune Response DADP Biosynthetic Process Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Wnt Signaling Pathway Involved In Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Apoptotic DNA Fragmentation Cellular Response To Potassium Ion Starvation L-asparagine Biosynthetic Process	Intrinsic Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Cell Death Death Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Execution Phase Of Apoptosis Positive Regulation Of Apoptotic Process Regulation Of Mitochondrion Organization Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Protein Processing Activation Of Cysteine-type Endopeptidase Activity Regulation Of Apoptotic Process Zymogen Activation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Regulation Of Cell Death Positive Regulation Of Organelle Organization Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Apoptotic DNA Fragmentation Positive Regulation Of Peptidase Activity Intracellular Signal Transduction Cytolysis Apoptotic Nuclear Changes Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Intracellular Transport Positive Regulation Of Proteolysis Regulation Of Organelle Organization Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Regulation Of Cellular Component Organization DNA Catabolic Process, Endonucleolytic Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Intracellular Transport Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Signal Transduction Negative Regulation Of Protein Serine/threonine Kinase Activity DNA Catabolic Process Golgi Reassembly Apoptotic Chromosome Condensation Granzyme-mediated Apoptotic Signaling Pathway Regulation Of Proteolysis Regulation Of Establishment Of Protein Localization
Tagcloud ?			cd40 cd71 dysplastic effector erythroid erythropoiesis etv6 fas glya gm hematopoiesis hemoglobin ineffective leukemic making megakaryocyte meps microrna mir9 mirna mirnas profiling progenitors robust runx1 sorted speculating sub ut
Tagcloud (Difference) ?			cd40 cd71 dysplastic effector erythroid erythropoiesis etv6 fas glya gm hematopoiesis hemoglobin ineffective leukemic making megakaryocyte meps microrna mir9 mirna mirnas profiling progenitors robust runx1 sorted speculating sub ut
Tagcloud (Intersection) ?