HSPH1 and NMI

Number of citations of the paper that reports this interaction (PubMedID 25088258)
0

Data Source:
BioGRID (pull down)

		HSPH1	NMI
Description		heat shock protein family H (Hsp110) member 1	N-myc and STAT interactor
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Protein-containing Complex Extracellular Exosome Endocytic Vesicle Lumen	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Nucleotide Binding Adenyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding Alpha-tubulin Binding ATP-dependent Protein Folding Chaperone	Protein Binding Identical Protein Binding
	Biological Process	Protein Folding Response To Unfolded Protein Positive Regulation Of MHC Class I Biosynthetic Process Positive Regulation Of NK T Cell Activation	Macrophage Activation Involved In Immune Response Immune System Process Cell Surface Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Type I Interferon Production Negative Regulation Of Interferon-alpha Production Negative Regulation Of Interferon-beta Production Toll-like Receptor 4 Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Positive Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Protein K48-linked Ubiquitination Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Protein K48-linked Ubiquitination
Pathways		Scavenging by Class F Receptors Scavenging by Class F Receptors Regulation of HSF1-mediated heat shock response	SARS-CoV-1 activates/modulates innate immune responses
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		20 interacting genes: ADD1 CEBPA CFL1 CHD3 CSNK2A1 CSNK2A2 DYNLRB1 FNDC3B HSPA13 HSPA8 NEDD8 NMI PAFAH1B1 PAFAH1B3 PGK1 PTEN STK39 TUBA4A UBA1 VAV2	57 interacting genes: ANKRD13C-DT BRAT1 BRCA1 BRMS1 C1orf216 CDKN2A CDKN2D CNKSR3 CNOT7 COPS7B CYP2E1 EMILIN1 EXOSC5 GCSH GOLGA8EP HDDC3 HGS HOXC9 HSPA8 HSPH1 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MCPH1 MORF4L1 MTMR6 MTMR9 MYC MYCN MYOM3 NECAP2 POMZP3 PSMA1 RYBP SCEL SFR1 SH3GLB2 SINHCAF SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 THAP8 TRAF5 TRIM72 TRIP12 TUBA3C TUBA3E TXLNA TXLNB UBE2I
Entrez ID		10808	9111
HPRD ID		09990	04632
Ensembl ID		ENSG00000120694	ENSG00000123609
Uniprot IDs		A0A0A0MSM0 B4DY72 Q92598	Q13287
PDB IDs		6GFA
Enriched GO Terms of Interacting Partners?		Regulation Of Proteolysis Regulation Of Cell Size Protein Kinase CK2 Complex 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Cytoplasm Regulation Of Cellular Component Size Cytosol Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Size Nucleotide Binding ATP Binding Protein Targeting To Vacuole Involved In Autophagy Microtubule Cytoskeleton Organization Positive Regulation Of Embryonic Development Cellular Response To Stress Microtubule-based Process PML Body PcG Protein Complex Protein Refolding Negative Regulation Of Cellular Component Organization Negative Regulation Of Supramolecular Fiber Organization Cytoskeleton Organization Negative Regulation Of Actin Filament Depolymerization Cellular Response To Metal Ion Protein Heterodimerization Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Protein Metabolic Process Cofilin-actin Rod Negative Regulation Of Unidimensional Cell Growth Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Cell Growth Positive Regulation Of Dendritic Spine Development Regulation Of Postsynapse Organization Positive Regulation Of Establishment Of Cell Polarity Regulating Cell Shape Protein Depolymerization Positive Regulation Of Barbed-end Actin Filament Capping Negative Regulation Of Cell Projection Organization Positive Regulation Of Protein Localization To Cell Leading Edge Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Chaperone-mediated Autophagy Translocation Complex Disassembly ATP-dependent Protein Folding Chaperone Dynein Intermediate Chain Binding Central Nervous System Neuron Axonogenesis Phosphoglycerate Kinase Activity Negative Regulation Of Synaptic Vesicle Clustering Positive Regulation Of Sodium Ion Import Across Plasma Membrane Response To Stress Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	Nucleoplasm Cell Surface Receptor Signaling Pathway Via JAK-STAT Growth Hormone Receptor Signaling Pathway Via JAK-STAT Cell Surface Receptor Signaling Pathway Via STAT Growth Hormone Receptor Signaling Pathway Interleukin-9-mediated Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Cell Population Proliferation RNA Polymerase II Transcription Regulator Complex Negative Regulation Of RNA Metabolic Process Negative Regulation Of Developmental Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleic Acid Metabolic Process Regulation Of Programmed Cell Death Regulation Of Erythrocyte Differentiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Cell Population Proliferation Development Of Secondary Female Sexual Characteristics Development Of Secondary Male Sexual Characteristics DNA-binding Transcription Factor Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Sin3-type Complex Regulation Of Apoptotic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Differentiation DNA-templated Transcription Positive Regulation Of Mesenchymal Cell Proliferation Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Negative Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Development Of Secondary Sexual Characteristics Positive Regulation Of Gene Expression Regulation Of Myeloid Cell Apoptotic Process Positive Regulation Of Metabolic Process
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