PEX6 and ATF7IP

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		PEX6	ATF7IP
Gene Name		peroxisomal biogenesis factor 6	activating transcription factor 7 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Peroxisome Peroxisomal Membrane Cytosol	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding ATPase Activity Protein Complex Binding ATPase Activity, Coupled	Transcription Corepressor Activity Protein Binding ATPase Activity
	Biological Process	Protein Targeting To Peroxisome Peroxisome Organization Metabolic Process Protein Import Into Peroxisome Matrix, Translocation Protein Stabilization	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Chromatin Organization Transcription, DNA-templated Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Pathways			Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		7 interactors: ATF7IP CERS2 PEX1 PEX26 RPL27A RPS14 SMAD3	68 interactors: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CSPG4 DISC1 DMTF1 DNM2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO3 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A
Entrez ID		5190	55729
HPRD ID		03293	09811
Ensembl ID		ENSG00000124587	ENSG00000171681
Uniprot IDs		Q13608 Q8WYQ1	B3KNI7 B3KQF8 F5GX74 G3V1U0 Q6VMQ6
PDB IDs			2RPQ
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization To Organelle Protein Targeting Protein Import Into Peroxisome Matrix Protein Localization To Organelle Viral Process Protein Targeting To Membrane Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Cytoplasmic Transport Establishment Of Protein Localization To Membrane Intracellular Protein Transport Peroxisome Organization Intracellular Protein Transmembrane Transport Protein Localization To Membrane Protein Transmembrane Transport Viral Transcription Positive Regulation Of Transforming Growth Factor Beta3 Production Cellular Protein Localization Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Protein Transport Establishment Of Protein Localization To Endoplasmic Reticulum Establishment Of Protein Localization Intracellular Transport Protein Localization To Endoplasmic Reticulum Microtubule-based Peroxisome Localization Translational Termination Nuclear-transcribed MRNA Catabolic Process Evasion Or Tolerance Of Host Defenses By Virus Protein Import MRNA Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Translational Elongation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly RNA Catabolic Process Protein Localization Cellular Protein Complex Disassembly Viral Life Cycle Regulation Of Extracellular Matrix Assembly Establishment Of Localization In Cell Membrane Organization Protein Complex Disassembly Regulation Of Gene Expression, Epigenetic Protein Import Into Peroxisome Membrane Primary MiRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Peroxisomal Membrane Transport	Transcription Initiation From RNA Polymerase II Promoter Viral Process Positive Regulation Of Viral Transcription Cell Differentiation DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Regulation Of Viral Transcription 7-methylguanosine RNA Capping Positive Regulation Of Viral Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation RNA Biosynthetic Process Developmental Process Transcription, DNA-templated Anatomical Structure Development Regulation Of Viral Process Post-Golgi Vesicle-mediated Transport Macromolecule Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Gene Expression RNA Metabolic Process Extracellular Matrix Disassembly Cellular Macromolecule Biosynthetic Process Anatomical Structure Morphogenesis System Development Cell Junction Assembly Cardiovascular System Development Stem Cell Differentiation Anatomical Structure Formation Involved In Morphogenesis Biosynthetic Process Nervous System Development Neurogenesis Angiogenesis Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Golgi To Plasma Membrane Protein Transport Somatic Stem Cell Maintenance Protein Sumoylation Positive Regulation Of Gene Expression Multicellular Organismal Development Generation Of Neurons Stem Cell Development Blood Vessel Development Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Axon Guidance Golgi Vesicle Transport Vasculature Development
Tagcloud ?		aat2 aptamer bacteriophage colocalization dci1 gpd1 importation mdh3 mpps ms2 nonperoxisomal npy1 organellar pcd1 pcs60 peroxisomal peroxisomes pex1 pex11 pex14 pex28 pex3 pex5 pex7 pex8 pox1 puf5 rbp rfp	acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Difference) ?		aat2 aptamer bacteriophage colocalization dci1 gpd1 importation mdh3 mpps ms2 nonperoxisomal npy1 organellar pcd1 pcs60 peroxisomal peroxisomes pex1 pex11 pex14 pex28 pex3 pex5 pex7 pex8 pox1 puf5 rbp rfp	acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Intersection) ?