PEX6 and RPL27A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PEX6	RPL27A
Gene Name		peroxisomal biogenesis factor 6	ribosomal protein L27a
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Peroxisome Peroxisomal Membrane Cytosol	Cytosol Membrane Cytosolic Large Ribosomal Subunit
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding ATPase Activity Protein Complex Binding ATPase Activity, Coupled	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Protein Targeting To Peroxisome Peroxisome Organization Metabolic Process Protein Import Into Peroxisome Matrix, Translocation Protein Stabilization	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Body mass index ( 20935630) Obesity ( 23563607)
Protein-Protein Interactions		7 interactors: ATF7IP CERS2 PEX1 PEX26 RPL27A RPS14 SMAD3	4 interactors: GTF2F2 PEX6 PRKACB SIAH1
Entrez ID		5190	6157
HPRD ID		03293	04701
Ensembl ID		ENSG00000124587	ENSG00000166441
Uniprot IDs		Q13608 Q8WYQ1	P46776
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization To Organelle Protein Targeting Protein Import Into Peroxisome Matrix Protein Localization To Organelle Viral Process Protein Targeting To Membrane Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Cytoplasmic Transport Establishment Of Protein Localization To Membrane Intracellular Protein Transport Peroxisome Organization Intracellular Protein Transmembrane Transport Protein Localization To Membrane Protein Transmembrane Transport Viral Transcription Positive Regulation Of Transforming Growth Factor Beta3 Production Cellular Protein Localization Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Protein Transport Establishment Of Protein Localization To Endoplasmic Reticulum Establishment Of Protein Localization Intracellular Transport Protein Localization To Endoplasmic Reticulum Microtubule-based Peroxisome Localization Translational Termination Nuclear-transcribed MRNA Catabolic Process Evasion Or Tolerance Of Host Defenses By Virus Protein Import MRNA Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Translational Elongation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly RNA Catabolic Process Protein Localization Cellular Protein Complex Disassembly Viral Life Cycle Regulation Of Extracellular Matrix Assembly Establishment Of Localization In Cell Membrane Organization Protein Complex Disassembly Regulation Of Gene Expression, Epigenetic Protein Import Into Peroxisome Membrane Primary MiRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Peroxisomal Membrane Transport	Response To Clozapine Regulation Of Protein Stability Protein Import Into Peroxisome Matrix, Translocation
Tagcloud ?		aat2 aptamer bacteriophage colocalization dci1 gpd1 importation mdh3 mpps ms2 nonperoxisomal npy1 organellar pcd1 pcs60 peroxisomal peroxisomes pex1 pex11 pex14 pex28 pex3 pex5 pex7 pex8 pox1 puf5 rbp rfp	arabidopsis coordinating defects developmental disrupted extraribosomal female fertility fully gametogenesis gametophyte heterogeneity insufficiency lesser ovule paralogs phenotypes progressive redundantly result reveal ribosomal ribosome sporophyte sterility thaliana
Tagcloud (Difference) ?		aat2 aptamer bacteriophage colocalization dci1 gpd1 importation mdh3 mpps ms2 nonperoxisomal npy1 organellar pcd1 pcs60 peroxisomal peroxisomes pex1 pex11 pex14 pex28 pex3 pex5 pex7 pex8 pox1 puf5 rbp rfp	arabidopsis coordinating defects developmental disrupted extraribosomal female fertility fully gametogenesis gametophyte heterogeneity insufficiency lesser ovule paralogs phenotypes progressive redundantly result reveal ribosomal ribosome sporophyte sterility thaliana
Tagcloud (Intersection) ?