NLK and KRTAP5-6

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NLK	KRTAP5-6
Gene Name		nemo-like kinase	keratin associated protein 5-6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Keratin Filament
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding SH2 Domain Binding
	Biological Process	MAPK Cascade Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Wnt Signaling Pathway Peptidyl-threonine Phosphorylation Negative Regulation Of Wnt Signaling Pathway Serine Phosphorylation Of STAT3 Protein Intracellular Signal Transduction Protein Autophosphorylation
Pathways		Ca2+ pathway Signaling by Wnt beta-catenin independent WNT signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: ASGR1 ATXN1 CHD7 CREBBP CUL1 FBXW5 FOXO4 GRN HIPK2 KRTAP10-3 KRTAP4-2 KRTAP5-6 KRTAP5-9 LEF1 MYB MYBL1 PPARG QRICH1 RCHY1 SDR16C5 SKP2 STAT3 STAT5A USP4 ZHX3	26 interactors: ADAMTSL4 CATSPER1 CREB5 GLRX3 HOXA1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 MEOX2 NLK NOTCH2NL NUFIP2 OTX1 PLSCR1 RGS20 SMCP SPRY2
Entrez ID		51701	440023
HPRD ID		17637	17250
Ensembl ID		ENSG00000087095	ENSG00000205864
Uniprot IDs		Q9UBE8	Q6L8G9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Leukocyte Differentiation Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Hemopoiesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Immune System Development Radial Glial Cell Differentiation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Developmental Process Lymphocyte Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Gene Expression Anatomical Structure Development Modification-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Multicellular Organism Growth Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Protein Catabolic Process Cellular Response To Oxygen Levels Organ Development Regulation Of Cell Cycle Cellular Response To Hormone Stimulus	Inner Ear Morphogenesis Ear Morphogenesis Positive Regulation Of Gene Expression Inner Ear Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Ear Development Anterior/posterior Pattern Specification Sperm Motility Optokinetic Behavior Abducens Nerve Formation Positive Regulation Of Transcription, DNA-templated Embryonic Organ Morphogenesis Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Facial Nucleus Development Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Rhombomere 4 Development Semicircular Canal Formation Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Serine Phosphorylation Of STAT3 Protein Rhombomere 3 Development Rhombomere 5 Development Pattern Specification Process Metencephalon Development Macromolecule Biosynthetic Process Embryonic Organ Development Single Fertilization Serine Phosphorylation Of STAT Protein Regulation Of Transcription From RNA Polymerase II Promoter Somite Specification Phosphatidylserine Biosynthetic Process Embryo Development Sensory Perception Of Sound Diencephalon Morphogenesis Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Sensory Organ Development Penetration Of Zona Pellucida Lung Growth Hindbrain Development Fertilization Embryonic Neurocranium Morphogenesis Sensory Perception Of Mechanical Stimulus Regulation Of Neurotrophin TRK Receptor Signaling Pathway Embryonic Morphogenesis
Tagcloud ?		adenomatosis apr asymmetric asymmetry caenorhabditis divisions evolutionarily fates heterochronic illuminate lin lineages lit opposing pharynx polarity polarizing polyposis pop postembryonic proceeds renewing robustly seam symmetric tcf timing transitions wingless
Tagcloud (Difference) ?		adenomatosis apr asymmetric asymmetry caenorhabditis divisions evolutionarily fates heterochronic illuminate lin lineages lit opposing pharynx polarity polarizing polyposis pop postembryonic proceeds renewing robustly seam symmetric tcf timing transitions wingless
Tagcloud (Intersection) ?