NLK and MYBL1

Number of citations of the paper that reports this interaction (PMID 16055500)
13

Data Source:
BioGRID (enzymatic study)

		NLK	MYBL1
Gene Name		nemo-like kinase	v-myb avian myeloblastosis viral oncogene homolog-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding SH2 Domain Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding
	Biological Process	MAPK Cascade Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Wnt Signaling Pathway Peptidyl-threonine Phosphorylation Negative Regulation Of Wnt Signaling Pathway Serine Phosphorylation Of STAT3 Protein Intracellular Signal Transduction Protein Autophosphorylation	Transcription, DNA-templated Gene Expression PiRNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Ca2+ pathway Signaling by Wnt beta-catenin independent WNT signaling	PIWI-interacting RNA (piRNA) biogenesis Regulatory RNA pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: ASGR1 ATXN1 CHD7 CREBBP CUL1 FBXW5 FOXO4 GRN HIPK2 KRTAP10-3 KRTAP4-2 KRTAP5-6 KRTAP5-9 LEF1 MYB MYBL1 PPARG QRICH1 RCHY1 SDR16C5 SKP2 STAT3 STAT5A USP4 ZHX3	4 interactors: CREBBP HIPK2 NCL NLK
Entrez ID		51701	4603
HPRD ID		17637	08868
Ensembl ID		ENSG00000087095	ENSG00000185697
Uniprot IDs		Q9UBE8	P10243 Q495G0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Leukocyte Differentiation Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Hemopoiesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Immune System Development Radial Glial Cell Differentiation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Developmental Process Lymphocyte Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Gene Expression Anatomical Structure Development Modification-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Multicellular Organism Growth Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Protein Catabolic Process Cellular Response To Oxygen Levels Organ Development Regulation Of Cell Cycle Cellular Response To Hormone Stimulus	Peptidyl-threonine Phosphorylation Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Peptidyl-serine Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-amino Acid Modification Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta N-terminal Peptidyl-lysine Acetylation Serine Phosphorylation Of STAT3 Protein Voluntary Musculoskeletal Movement Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Transcription, DNA-templated PML Body Organization Serine Phosphorylation Of STAT Protein Response To Hypoxia Germ-line Stem Cell Maintenance Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Iris Morphogenesis Lens Induction In Camera-type Eye Positive Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Gene Expression N-terminal Protein Amino Acid Acetylation Regulation Of Nitrogen Compound Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Embryonic Retina Morphogenesis In Camera-type Eye Viral Process Regulation Of Transcription From RNA Polymerase I Promoter Transcription, DNA-templated Cellular Response To Growth Factor Stimulus Response To Growth Factor Modulation By Virus Of Host Morphology Or Physiology RNA Biosynthetic Process Anatomical Structure Morphogenesis Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Embryonic Morphogenesis Retina Layer Formation N-terminal Protein Amino Acid Modification Positive Regulation Of Cellular Metabolic Process Lens Morphogenesis In Camera-type Eye
Tagcloud ?		adenomatosis apr asymmetric asymmetry caenorhabditis divisions evolutionarily fates heterochronic illuminate lin lineages lit opposing pharynx polarity polarizing polyposis pop postembryonic proceeds renewing robustly seam symmetric tcf timing transitions wingless	adenosarcoma appearing atrx britain cdk4 cnvs confirmation copyright diagnose exonic hmga2 interrogating introns ireland john ltd ma mdm2 mullerian overgrowth pathobiology pik3ca rearrangements sarcomatous sons stroma tools uncommon wiley
Tagcloud (Difference) ?		adenomatosis apr asymmetric asymmetry caenorhabditis divisions evolutionarily fates heterochronic illuminate lin lineages lit opposing pharynx polarity polarizing polyposis pop postembryonic proceeds renewing robustly seam symmetric tcf timing transitions wingless	adenosarcoma appearing atrx britain cdk4 cnvs confirmation copyright diagnose exonic hmga2 interrogating introns ireland john ltd ma mdm2 mullerian overgrowth pathobiology pik3ca rearrangements sarcomatous sons stroma tools uncommon wiley
Tagcloud (Intersection) ?