NLK and SDR16C5

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NLK	SDR16C5
Gene Name		nemo-like kinase	short chain dehydrogenase/reductase family 16C, member 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding SH2 Domain Binding	Retinol Dehydrogenase Activity
	Biological Process	MAPK Cascade Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Wnt Signaling Pathway Peptidyl-threonine Phosphorylation Negative Regulation Of Wnt Signaling Pathway Serine Phosphorylation Of STAT3 Protein Intracellular Signal Transduction Protein Autophosphorylation	Retinol Metabolic Process Retinal Metabolic Process Keratinocyte Proliferation Detection Of Light Stimulus Involved In Visual Perception Oxidation-reduction Process
Pathways		Ca2+ pathway Signaling by Wnt beta-catenin independent WNT signaling	Signaling by Retinoic Acid RA biosynthesis pathway
Drugs
Diseases
GWAS			Height ( 20881960)
Protein-Protein Interactions		25 interactors: ASGR1 ATXN1 CHD7 CREBBP CUL1 FBXW5 FOXO4 GRN HIPK2 KRTAP10-3 KRTAP4-2 KRTAP5-6 KRTAP5-9 LEF1 MYB MYBL1 PPARG QRICH1 RCHY1 SDR16C5 SKP2 STAT3 STAT5A USP4 ZHX3	2 interactors: EXTL1 NLK
Entrez ID		51701	195814
HPRD ID		17637	12351
Ensembl ID		ENSG00000087095	ENSG00000170786
Uniprot IDs		Q9UBE8	B3KT84 Q8N3Y7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Leukocyte Differentiation Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Hemopoiesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Immune System Development Radial Glial Cell Differentiation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Developmental Process Lymphocyte Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Gene Expression Anatomical Structure Development Modification-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Multicellular Organism Growth Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Protein Catabolic Process Cellular Response To Oxygen Levels Organ Development Regulation Of Cell Cycle Cellular Response To Hormone Stimulus	Serine Phosphorylation Of STAT3 Protein Serine Phosphorylation Of STAT Protein
Tagcloud ?		adenomatosis apr asymmetric asymmetry caenorhabditis divisions evolutionarily fates heterochronic illuminate lin lineages lit opposing pharynx polarity polarizing polyposis pop postembryonic proceeds renewing robustly seam symmetric tcf timing transitions wingless	annotation cbs degs description devastating diffuse downloaded etiology foundation fpr1 gse idiopathic iips il1r2 interstitial kinds mgam mt1x parenchymal played pneumonias ppi profiling s100a12 screened serpina3 slco4a1 subtypes underscores
Tagcloud (Difference) ?		adenomatosis apr asymmetric asymmetry caenorhabditis divisions evolutionarily fates heterochronic illuminate lin lineages lit opposing pharynx polarity polarizing polyposis pop postembryonic proceeds renewing robustly seam symmetric tcf timing transitions wingless	annotation cbs degs description devastating diffuse downloaded etiology foundation fpr1 gse idiopathic iips il1r2 interstitial kinds mgam mt1x parenchymal played pneumonias ppi profiling s100a12 screened serpina3 slco4a1 subtypes underscores
Tagcloud (Intersection) ?