KRTAP5-6 and NOTO

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP5-6	NOTO
Description		keratin associated protein 5-6	notochord homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Chromatin Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Heart Looping Regulation Of Transcription By RNA Polymerase II Determination Of Left/right Symmetry Central Nervous System Development Brain Development Embryonic Pattern Specification Dorsal/ventral Pattern Formation Neuron Differentiation Notochord Development Motile Cilium Assembly Regulation Of Cilium Assembly
Pathways		Keratinization	Formation of axial mesoderm
Drugs
Diseases
GWAS		Logical memory (delayed recall) in mild cognitive impairment ( 29274321)	General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435)
Interacting Genes		93 interacting genes: ADAM12 ADAMTSL4 CATSPER1 CCN3 COL8A1 CRCT1 CREB5 CYSRT1 DDIT4L GLRX3 GUCD1 HOXA1 INCA1 KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-3 KRTAP13-3 KRTAP17-1 KRTAP26-1 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-1 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LBX1 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LINGO1 MAPKBP1 MEOX2 MYPOP NBPF19 NLK NOTCH2NLA NOTO NR1D2 NR4A3 NUFIP2 OTX1 OXER1 PLSCR1 POU4F2 RGS17 RGS19 RGS20 SMCP SPRY2 TRIM42 VASN VGLL3 YY1	31 interacting genes: ANKRD11 APOBEC1 BAG3 BANP BTF3 CCDC120 CEP19 CHAF1A EIPR1 ETV3L FAM9B FOXD2 FOXH1 GLYCTK HNRNPK IP6K3 KRT34 KRTAP19-7 KRTAP5-6 KRTAP6-1 KRTAP6-3 LDLRAP1 LRP10 MAGED1 MEIS2 NKX2-4 PIH1D2 POU4F2 SBK3 TTC23 UBTFL1
Entrez ID		440023	344022
HPRD ID		17250
Ensembl ID		ENSG00000205864	ENSG00000214513
Uniprot IDs		Q6L8G9	A8MTQ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Protein Binding Identical Protein Binding Cytosol	Intermediate Filament Positive Regulation Of Low-density Lipoprotein Particle Clearance Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Low-density Lipoprotein Particle Clearance
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