JKAMP and GPR37

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		JKAMP	GPR37
Description		JNK1/MAPK8 associated membrane protein	G protein-coupled receptor 37
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Ubiquitin Ligase Complex Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Cell Surface Membrane Dendrite Cell Projection Receptor Complex Synapse
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	G Protein-coupled Receptor Activity Protein Binding Neuropeptide Receptor Activity G Protein-coupled Peptide Receptor Activity PDZ Domain Binding Hsp70 Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Prosaposin Receptor Activity Peptide Binding Neuropeptide Binding
	Biological Process	Response To Unfolded Protein ERAD Pathway	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Dendrite Development Locomotion Involved In Locomotory Behavior Cellular Response To Reactive Oxygen Species Dopamine Biosynthetic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Dopamine Metabolic Process
Pathways			Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Ankylosing spondylitis ( 23749187) Cutaneous malignant melanoma ( 26237428 32341527) Nevus count or cutaneous melanoma ( 32341527) Reading and spelling ( 23738518) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: AGTR1 CRYAA GPR37 MAPK8 RNF5 YIPF6	51 interacting genes: ADGRB1 ADORA2A ADRA1A ADRB2 BNIP3 CCNQ CNTN1 DRD2 ERGIC3 FA2H FKBP8 FUCA2 G6PC3 GABARAPL2 GABBR1 GHITM GLP1R GPR17 GRIP1 HDGF HLA-C HSP90B1 HSPA1A HTR2C HTR4 IFITM3 JKAMP LTB4R2 P4HTM PPM1J PRKN SDCBP SLC37A1 SLC3A2 SLC41A3 SLC8A2 SPATA2L STUB1 SYVN1 TAFA5 TMED1 TMEM161A TMEM175 TMEM231 TMEM63A TTYH1 TTYH2 WLS YIF1A YIF1B ZDHHC11
Entrez ID		51528	2861
HPRD ID		12623	03992
Ensembl ID		ENSG00000050130	ENSG00000170775
Uniprot IDs		B3KPC2 G3V2M4 Q9P055	O15354
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Reactive Oxygen Species Angiotensin Type I Receptor Activity Response To Oxidative Stress JUN Phosphorylation Response To Stress Angiotensin Type II Receptor Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Phospholipase C-activating Angiotensin-activated Signaling Pathway Bradykinin Receptor Binding Renin-angiotensin Regulation Of Aldosterone Production Response To UV Lens Fiber Cell Morphogenesis Prosaposin Receptor Activity Cellular Response To Reactive Oxygen Species Positive Regulation Of Dopamine Metabolic Process Cellular Response To Oxidative Stress Locomotion Involved In Locomotory Behavior JUN Kinase Activity Histone Deacetylase Regulator Activity Basal Dendrite Ubiquitin-like Protein Conjugating Enzyme Binding Regulation Of Renal Sodium Excretion Golgi Trans Cisterna	Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway COPII-coated ER To Golgi Transport Vesicle Regulation Of Catecholamine Secretion Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Dendrite ERAD Pathway Synaptic Transmission, Dopaminergic Regulation Of Autophagy Of Mitochondrion Cell Communication Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Chemical Synaptic Transmission Regulation Of Membrane Potential Regulation Of Dopamine Secretion Cell-cell Signaling Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Signal Transduction Trans-synaptic Signaling Signaling Regulation Of Amine Transport Synaptic Signaling Modulation Of Chemical Synaptic Transmission Neuron-glial Cell Signaling Response To Psychosocial Stress Cellular Localization Synapse Positive Regulation Of Autophagy Of Mitochondrion Golgi Membrane Negative Regulation Of Dopamine Secretion Transmembrane Transport Response To Endoplasmic Reticulum Stress G Protein-coupled Receptor Binding Cellular Response To Topologically Incorrect Protein Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Glucose-6-phosphate Transport Volume-sensitive Chloride Channel Activity Establishment Of Localization In Cell Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Neurotransmitter Uptake Volume-sensitive Anion Channel Activity Regulation Of Synaptic Transmission, GABAergic Intracellular Transport Plasma Membrane Calcium Ion Transmembrane Import Into Cytosol Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Mitochondrial Fusion
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