PDE6G and L3MBTL3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PDE6G	L3MBTL3
Gene Name		phosphodiesterase 6G, cGMP-specific, rod, gamma	l(3)mbt-like 3 (Drosophila)
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Photoreceptor Disc Membrane	Nucleus
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Spectrin Binding CGMP Binding 3',5'-cyclic-GMP Phosphodiesterase Activity	Molecular_function
	Biological Process	Activation Of MAPK Activity Visual Perception Phototransduction, Visible Light Metabolic Process Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Negative Regulation Of Catalytic Activity Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Chromatin Modification Macrophage Differentiation Granulocyte Differentiation Erythrocyte Maturation
Pathways		Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Visual phototransduction Ca2+ pathway The phototransduction cascade Signaling by Wnt Diseases associated with visual transduction beta-catenin independent WNT signaling
Drugs
Diseases
GWAS			Height ( 20881960 23563607 18391951)
Protein-Protein Interactions		10 interactors: ADRBK1 BHLHE40 DNM2 FNBP1 GNAO1 GRB2 L3MBTL3 MAPK3 SRC TRIP10	26 interactors: ASB6 BANP BYSL KDM1A LRRK2 LSM4 LZTR1 MAPK3 MAPK9 MORF4L1 MORF4L2 NGB OAZ3 PDE6G PHC2 PIK3R3 PLEKHF1 PLEKHF2 POLR2L PRKAA1 PRKAA2 SNRPB SP100 SUMO1P1 THRA TTC19
Entrez ID		5148	84456
HPRD ID		08914	11222
Ensembl ID		ENSG00000185527	ENSG00000198945
Uniprot IDs		P18545	Q96JM7
PDB IDs		3JWR	1WJQ 1WJS 3UT1 4FL6 4L59
Enriched GO Terms of Interacting Partners?		Endocytosis Vesicle-mediated Transport Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Receptor Internalization Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Receptor Metabolic Process Receptor-mediated Endocytosis Regulation Of Early Endosome To Late Endosome Transport Neuron Projection Development Neuron Development Cell Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Neuron Differentiation Cell Projection Organization Platelet Activation Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Response To Insulin Stimulus Small GTPase Mediated Signal Transduction Immune System Process Ras Protein Signal Transduction Neuron Projection Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Peptidyl-tyrosine Autophosphorylation Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Insulin Generation Of Neurons Innate Immune Response Cellular Response To Peptide Hormone Stimulus Response To Organonitrogen Compound Cell Projection Morphogenesis Cellular Response To Peptide Cell Part Morphogenesis Neurogenesis Enzyme Linked Receptor Protein Signaling Pathway System Development Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Apolipoprotein Binding Negative Regulation Of The Force Of Heart Contraction By Chemical Signal T Cell Costimulation Axon Guidance	Positive Regulation Of Autophagy Chromatin Modification Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Binding RNA Metabolic Process Regulation Of Autophagy Chromatin Organization Transcription, DNA-templated Positive Regulation Of Metabolic Process RNA Biosynthetic Process Regulation Of Lipid Metabolic Process Cellular Response To Stress Activation Of MAPK Activity Insulin Receptor Signaling Pathway Negative Regulation Of Protein Binding Negative Regulation Of Transport Chromosome Organization Gene Expression Positive Regulation Of MAP Kinase Activity Cellular Response To Insulin Stimulus Regulation Of Energy Homeostasis Regulation Of Apoptotic Process Positive Regulation Of Glycolytic Process Negative Regulation Of Intracellular Protein Transport Fatty Acid Homeostasis Positive Regulation Of Gene Expression Cellular Response To Organonitrogen Compound Regulation Of Cell Death Cellular Nitrogen Compound Metabolic Process Regulation Of Binding Regulation Of Circadian Rhythm Organelle Organization Response To Organonitrogen Compound Regulation Of Metabolic Process Activation Of Protein Kinase Activity Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity Nucleobase-containing Compound Metabolic Process Regulation Of MAP Kinase Activity Response To Insulin Negative Regulation Of Intracellular Transport Histone-serine Phosphorylation Regulation Of Signal Transduction Peptidyl-serine Phosphorylation Regulation Of Intracellular Signal Transduction Cellular Response To Peptide Hormone Stimulus Cellular Response To Hormone Stimulus Response To Stress Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Glucose Starvation
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