PDE6G

Gene Name		phosphodiesterase 6G, cGMP-specific, rod, gamma
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Photoreceptor Disc Membrane
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Spectrin Binding CGMP Binding 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Activation Of MAPK Activity Visual Perception Phototransduction, Visible Light Metabolic Process Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Negative Regulation Of Catalytic Activity Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Pathways		Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Visual phototransduction Ca2+ pathway The phototransduction cascade Signaling by Wnt Diseases associated with visual transduction beta-catenin independent WNT signaling
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: ADRBK1 BHLHE40 DNM2 FNBP1 GNAO1 GRB2 L3MBTL3 MAPK3 SRC TRIP10
Entrez ID		5148
HPRD ID		08914
Ensembl ID		ENSG00000185527
Uniprot IDs		P18545
PDB IDs		3JWR
Enriched GO Terms of Interacting Partners?		Endocytosis Vesicle-mediated Transport Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Receptor Internalization Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Receptor Metabolic Process Receptor-mediated Endocytosis Regulation Of Early Endosome To Late Endosome Transport Neuron Projection Development Neuron Development Cell Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Neuron Differentiation Cell Projection Organization Platelet Activation Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Response To Insulin Stimulus Small GTPase Mediated Signal Transduction Immune System Process Ras Protein Signal Transduction Neuron Projection Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Peptidyl-tyrosine Autophosphorylation Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Insulin Generation Of Neurons Innate Immune Response Cellular Response To Peptide Hormone Stimulus Response To Organonitrogen Compound Cell Projection Morphogenesis Cellular Response To Peptide Cell Part Morphogenesis Neurogenesis Enzyme Linked Receptor Protein Signaling Pathway System Development Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Apolipoprotein Binding Negative Regulation Of The Force Of Heart Contraction By Chemical Signal T Cell Costimulation Axon Guidance
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