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PDE6G and TRIP10
Number of citations of the paper that reports this interaction (PubMedID
14502124
)
0
Data Source:
HPRD
(in vitro, two hybrid)
PDE6G
TRIP10
Description
phosphodiesterase 6G
thyroid hormone receptor interactor 10
Image
GO Annotations
Cellular Component
Plasma Membrane
Photoreceptor Outer Segment Membrane
Photoreceptor Disc Membrane
Phagocytic Cup
Nucleoplasm
Cytoplasm
Lysosome
Golgi Apparatus
Cytosol
Cytoskeleton
Plasma Membrane
Cell Cortex
Membrane
Cell Projection
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
3',5'-cyclic-nucleotide Phosphodiesterase Activity
Enzyme Inhibitor Activity
Protein Binding
Hydrolase Activity
Spectrin Binding
CGMP Binding
3',5'-cyclic-GMP Phosphodiesterase Activity
Protein Binding
Lipid Binding
Identical Protein Binding
Biological Process
Visual Perception
Positive Regulation Of MAPK Cascade
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of G Protein-coupled Receptor Signaling Pathway
Endocytosis
Cell Communication
Signal Transduction
Actin Cytoskeleton Organization
Pathways
Activation of the phototransduction cascade
Activation of the phototransduction cascade
Inactivation, recovery and regulation of the phototransduction cascade
Ca2+ pathway
Ca2+ pathway
Clathrin-mediated endocytosis
RHOQ GTPase cycle
Drugs
Sildenafil
Tadalafil
Vardenafil
3-isobutyl-1-methyl-7H-xanthine
Diseases
Retinitis pigmentosa (RP)
GWAS
Blond vs. brown/black hair color (
30531825
)
High myopia (
31816047
)
Refractive error (
32231278
)
Interacting Genes
11 interacting genes:
BHLHE40
DNM2
FNBP1
GNAO1
GRB2
GRK2
L3MBTL3
MAPK3
PRKAB2
SRC
TRIP10
43 interacting genes:
ABI1
ABL2
AKAP9
ARHGAP12
ARHGAP17
CDC42
CREBBP
CTNNB1
DNM2
DTX3
HOXC11
HTT
JRK
LYN
MEOX1
MEOX2
NKX2-5
PAX6
PDE6G
POT1
PRKACA
RHOJ
RHOQ
RIN1
RXRA
SF3A2
SH3BP1
SHANK3
SMARCE1
SMURF1
SRC
STAT3
TERF1
THAP1
THRB
TINF2
UTF1
WAS
WASF1
WASL
WBP11
WWP2
ZBTB7B
Entrez ID
5148
9322
HPRD ID
08914
05142
Ensembl ID
ENSG00000185527
ENSG00000125733
Uniprot IDs
P18545
Q15642
W4VSQ9
PDB IDs
3JWR
2CT4
2EFK
2KE4
Enriched GO Terms of Interacting Partners
?
Import Into Cell
Endocytosis
Epidermal Growth Factor Receptor Signaling Pathway
Receptor Internalization
ERBB Signaling Pathway
Vesicle-mediated Transport
Actin Cytoskeleton Organization
Schwann Cell Development
Regulation Of Early Endosome To Late Endosome Transport
Contractile Actin Filament Bundle Assembly
Stress Fiber Assembly
ERBB2 Signaling Pathway
Actin Filament-based Process
Phagocytic Cup
Ephrin Receptor Binding
Receptor-mediated Endocytosis
Cell Cortex
Insulin-like Growth Factor Receptor Signaling Pathway
Regulation Of Heart Contraction
Signal Transduction
Podosome
Negative Regulation Of Immune Response
Protein Domain Specific Binding
T Cell Costimulation
Phosphotyrosine Residue Binding
Nucleotide Binding
Peptidyl-tyrosine Phosphorylation
Plasma Membrane
Negative Regulation Of Relaxation Of Smooth Muscle
Regulation Of Blood Circulation
Negative Regulation Of The Force Of Heart Contraction By Chemical Signal
Guanyl-nucleotide Exchange Factor Adaptor Activity
Cellular Response To Nutrient Levels
Actin Filament Bundle Assembly
Glial Cell Development
TORC1 Signaling
Actin Filament Bundle Organization
Negative Regulation Of TORC1 Signaling
Autophagy
Clathrin-coated Pit
Caveola
Edg-2 Lysophosphatidic Acid Receptor Binding
Negative Regulation Of Membrane Tubulation
Vesicle Scission
Mu-type Opioid Receptor Binding
Insulin Receptor Signaling Pathway
Grb2-EGFR Complex
Pristanate-CoA Ligase Activity
Phytanate-CoA Ligase Activity
Cholate-CoA Ligase Activity
Positive Regulation Of Cellular Component Organization
Actin Filament Organization
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Cellular Component Organization
Positive Regulation Of Metabolic Process
Supramolecular Fiber Organization
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Organelle Organization
SH3 Domain Binding
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Metabolic Process
Anatomical Structure Morphogenesis
Positive Regulation Of Cell Projection Organization
Shelterin Complex
Positive Regulation Of Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Signal Transduction
Regulation Of Cell Projection Organization
Transcription By RNA Polymerase II
Actin Filament-based Process
Positive Regulation Of Macromolecule Biosynthetic Process
DNA-templated Transcription
Regulation Of Nucleobase-containing Compound Metabolic Process
Transmembrane Transporter Binding
Nuclear Telomere Cap Complex
Developmental Process
Regulation Of Actin Cytoskeleton Organization
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Telomere Maintenance
Actin Cytoskeleton Organization
Intracellular Signal Transduction
Regulation Of Primary Metabolic Process
Telomere Capping
Signal Transduction
Positive Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Positive Regulation Of Signal Transduction
Establishment Of Organelle Localization
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Cytoskeleton Organization
Membrane Invagination
Ectoderm Development
Regulation Of Cell Communication
Regulation Of Signaling
Cell Projection Morphogenesis
Positive Regulation Of DNA Metabolic Process
Intracellular Signaling Cassette
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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