CRLF3 and VPS25

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CRLF3	VPS25
Gene Name		cytokine receptor-like factor 3	vacuolar protein sorting 25 homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane	ESCRT II Complex Nucleus Nucleoplasm Nucleolus Mitochondrion Cytosol Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function		Structural Molecule Activity Protein Binding Protein Homodimerization Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of JAK-STAT Cascade Positive Regulation Of Cell Cycle Arrest	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Endosomal Transport Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization
Pathways			Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Height ( 18391951)
Protein-Protein Interactions		3 interactors: KDM1A LGALS14 VPS25	10 interactors: APIP BEND5 CHMP6 CRLF3 REL RHOXF2 SNF8 SPRY2 TRIM27 VPS36
Entrez ID		51379	84313
HPRD ID		16757	14396
Ensembl ID		ENSG00000176390	ENSG00000131475
Uniprot IDs		Q8IUI8	Q9BRG1
PDB IDs			2ZME 3CUQ 3HTU
Enriched GO Terms of Interacting Partners?		Regulation Of Primitive Erythrocyte Differentiation Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Endosome Transport Via Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Protein Targeting To Vacuole Regulation Of Histone H3-K4 Methylation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Establishment Of Protein Localization To Vacuole Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hormone Biosynthetic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Lysine Demethylation Regulation Of Hormone Metabolic Process Histone Demethylation Regulation Of Erythrocyte Differentiation Protein Demethylation Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of DNA Binding Regulation Of Histone Methylation Positive Regulation Of Neural Precursor Cell Proliferation Pituitary Gland Development Negative Regulation Of Protein Binding Demethylation Positive Regulation Of Stem Cell Proliferation Positive Regulation Of Myeloid Cell Differentiation Vacuolar Transport Regulation Of DNA Binding Negative Regulation Of Chromosome Organization Diencephalon Development	Endosomal Transport Vacuolar Transport Regulation Of Gene Expression Establishment Of Localization In Cell Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Interleukin-2 Secretion L-methionine Biosynthetic Process From S-adenosylmethionine Cellular Localization Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cytokine Production Protein Transport Establishment Of Protein Localization Intracellular Transport Mitotic Cell Cycle Process Regulation Of Transcription, DNA-templated S-adenosylmethionine Cycle Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Calcium Ion Import Endosome Transport Via Multivesicular Body Sorting Pathway Mitotic Cell Cycle Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Late Endosome To Vacuole Transport Regulation Of Intracellular Signal Transduction Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Kinase Activity Lung Growth Interferon-gamma Secretion L-methionine Biosynthetic Process From Methylthioadenosine Regulation Of Transcription From RNA Polymerase II Promoter Membrane Organization Negative Regulation Of Kinase Activity Regulation Of Neurotrophin TRK Receptor Signaling Pathway Protein Localization L-methionine Salvage Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Positive Regulation Of Interleukin-12 Biosynthetic Process Bud Elongation Involved In Lung Branching Negative Regulation Of Cell Death Negative Regulation Of Transferase Activity Cell Cycle Process Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Protein Phosphorylation Establishment Of Organelle Localization Methionine Biosynthetic Process Regulation Of Interleukin-12 Biosynthetic Process
Tagcloud ?		applicable biogenesis btb btbd9 clones detail easily elusive head legs microvesicles morphogenesis morphology nervous pc12 phenotypes pheochromocytoma poz restless slmvs ssbp3 stranded synaptic theoretically transport trapped uncovering vesicle vesicles	bmp consequent contexts directs endosomal endosome enu escrt fgf fgfr gestation hyperactivation hypomorphic limbs machineries mutagenesis mysterious patterning polydactylous polydactyly preferential shh sort sorting specification survive unperturbed vacuolar vertebrate
Tagcloud (Difference) ?		applicable biogenesis btb btbd9 clones detail easily elusive head legs microvesicles morphogenesis morphology nervous pc12 phenotypes pheochromocytoma poz restless slmvs ssbp3 stranded synaptic theoretically transport trapped uncovering vesicle vesicles	bmp consequent contexts directs endosomal endosome enu escrt fgf fgfr gestation hyperactivation hypomorphic limbs machineries mutagenesis mysterious patterning polydactylous polydactyly preferential shh sort sorting specification survive unperturbed vacuolar vertebrate
Tagcloud (Intersection) ?