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PCSK5 and KRTAP4-12
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PCSK5
KRTAP4-12
Gene Name
proprotein convertase subtilisin/kexin type 5
keratin associated protein 4-12
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Golgi Apparatus
Golgi Lumen
Integral Component Of Membrane
Secretory Granule
Keratin Filament
Molecular Function
Serine-type Endopeptidase Activity
Peptidase Activity
Peptide Binding
Protein Binding
Biological Process
Kidney Development
Renin Secretion Into Blood Stream
Signal Peptide Processing
Proteolysis
Cell-cell Signaling
Heart Development
Embryo Implantation
Anterior/posterior Pattern Specification
Protein Processing
Peptide Hormone Processing
Viral Life Cycle
Respiratory Tube Development
Nerve Growth Factor Processing
Limb Morphogenesis
Cytokine Biosynthetic Process
Peptide Biosynthetic Process
Neurotrophin TRK Receptor Signaling Pathway
Embryonic Digestive Tract Development
Embryonic Skeletal System Development
Pathways
Signalling by NGF
NGF processing
Drugs
Diseases
GWAS
Amyotrophic lateral sclerosis (age of onset) (
22959728
)
Height (
20881960
23563607
)
Metabolite levels (5-HIAA) (
23319000
)
Response to fenofibrate (adiponectin levels) (
23149075
)
Total ventricular volume (
21116278
)
Protein-Protein Interactions
20 interactors:
AMH
APPBP2
ATN1
CACNA1A
GLRX3
HOXA1
ITGA6
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP4-12
KRTAP5-9
LCE3C
MEOX2
NOTCH2NL
NUFIP2
PMCH
PTPRM
REN
STK16
107 interactors:
ADAMTSL4
ALPP
AQP1
ATG12
ATN1
BAHD1
BEX2
C10orf62
C19orf66
CATSPER1
CBX2
CCDC116
CCDC185
CCNK
CDC42EP1
CHCHD3
CHIC2
CLDN2
CNNM3
CNTFR
COL8A1
CRCT1
CREB5
CRY1
DBF4B
DLK2
EIF4E2
FAM107A
FAM27E3
FAM76B
FBXL18
FBXW5
GLRX3
GNE
GPATCH2L
GPRIN2
GRAP2
HHEX
HOXA1
HOXB9
IFI30
ILF3
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP26-1
KRTAP3-2
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE1B
LCE2D
LCE3E
LCE4A
LINGO1
LNX1
MAPKBP1
MEOX2
MRPL4
NOTCH2NL
NPDC1
NUDT18
NUFIP2
OTX1
PCSK5
PDGFRB
PFKL
PHLDA1
PLSCR1
PLSCR4
PNKP
PRKAB2
PRR13
QPRT
RERE
RPS28
SLC25A10
SLC25A6
SMCP
SPATA3
SPG7
SPRY2
TAP1
TBC1D16
TBC1D23
TCEB3B
THAP10
THAP7
TOP3B
TXNDC5
ZBTB16
ZNF165
ZNF20
ZNF250
ZNF408
ZNF415
ZNF417
ZNF426
ZNF439
ZNF440
ZNF581
ZNF638
ZNF655
ZNF764
ZSCAN26
Entrez ID
5125
83755
HPRD ID
08985
13941
Ensembl ID
ENSG00000099139
ENSG00000213416
Uniprot IDs
Q92824
Q9BQ66
PDB IDs
Enriched GO Terms of Interacting Partners
?
Developmental Process
Multicellular Organismal Development
Pons Development
Cell Differentiation
Anatomical Structure Development
Organ Development
System Development
Tissue Development
Behavior
Neural Nucleus Development
Optokinetic Behavior
Cerebellar Molecular Layer Development
Abducens Nerve Formation
Neuron Death
Vestibular Nucleus Development
Facial Nucleus Development
Preantral Ovarian Follicle Growth
Urogenital System Development
Feeding Behavior
Positive Regulation Of Gene Expression
Rhombomere 4 Development
Cerebellum Maturation
Semicircular Canal Formation
Musculoskeletal Movement, Spinal Reflex Action
Anatomical Structure Morphogenesis
Rhombomere 3 Development
Rhombomere 5 Development
Gamma-aminobutyric Acid Secretion
Renin-angiotensin Regulation Of Aldosterone Production
Metencephalon Development
Neuromuscular Process
Regulation Of Acetylcholine Secretion, Neurotransmission
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Anatomical Structure Formation Involved In Morphogenesis
Response To Drug
Rhythmic Synaptic Transmission
Somite Specification
Ectodermal Cell Differentiation
Cell Development
Response To External Stimulus
Regulation Of Transcription From RNA Polymerase II Promoter
Oogenesis Stage
Cell Projection Organization
Drinking Behavior
Gonadal Mesoderm Development
Response To CGMP
Mullerian Duct Regression
Hindbrain Development
Cell Morphogenesis Involved In Neuron Differentiation
Calcium Ion-dependent Exocytosis Of Neurotransmitter
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Biosynthetic Process
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Metabolic Process
Regulation Of RNA Metabolic Process
Keratinization
Anterior/posterior Pattern Specification
Regulation Of Cellular Process
Regulation Of Metabolic Process
Cellular Process
Keratinocyte Differentiation
Embryo Development
Phospholipid Scrambling
Metanephric Glomerulus Vasculature Development
Pattern Specification Process
Metanephric Glomerulus Development
Epidermal Cell Differentiation
Epidermis Development
Mitochondrion Organization
Metabolic Process
Forebrain Morphogenesis
Transcription From RNA Polymerase II Promoter
Glomerulus Vasculature Development
Multicellular Organismal Development
Organic Anion Transport
Inner Ear Development
Cell Migration Involved In Coronary Angiogenesis
Hepatic Duct Development
Abducens Nerve Formation
Metanephric Mesenchymal Cell Migration
Transepithelial Water Transport
Renin Secretion Into Blood Stream
Metanephric Descending Thin Limb Development
DGDP Catabolic Process
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Tagcloud
?
angptl2
cldn10
cldn4
cst6
dioestrus
enpp1
epas1
itgb4
lgals1
lgals3bp
maged1
mep1b
metoestrus
muc16
oestrogens
oestrous
oestrus
plat
preoestrus
sepp1
simmental
slc11a2
slc16a1
slc1a1
tdgf1
tek
timp1
timp2
tjp1
Tagcloud (Difference)
?
angptl2
cldn10
cldn4
cst6
dioestrus
enpp1
epas1
itgb4
lgals1
lgals3bp
maged1
mep1b
metoestrus
muc16
oestrogens
oestrous
oestrus
plat
preoestrus
sepp1
simmental
slc11a2
slc16a1
slc1a1
tdgf1
tek
timp1
timp2
tjp1
Tagcloud (Intersection)
?