HSD17B11 and GOLT1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HSD17B11	GOLT1A
Description		hydroxysteroid 17-beta dehydrogenase 11	golgi transport 1A
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol	Golgi Cis Cisterna Golgi Membrane Nuclear Envelope Cytoplasm Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Cytosol Endomembrane System Membrane
	Molecular Function	Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor	Protein Binding
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Estrogen Biosynthetic Process Androgen Catabolic Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi
Pathways		Estrogen biosynthesis
Drugs		Aetiocholanolone
Diseases
GWAS		Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)	Metabolite levels ( 23823483) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		54 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SERPINE1 SFRP4 SFT2D2 SFXN3 SLC25A46 SLC30A8 SLC67A1 STRIT1 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VEZT YIPF6	26 interacting genes: ABHD16A AGPAT3 AQP6 C8A CCDC167 CLDND2 COX20 CPT1B FAXDC2 GPR152 GYPA HSD17B11 MGLL MSMO1 NAT8 NDUFA3 NRM OTULINL PLLP RNF24 SLC30A2 SLC35H1 TECR TIMM23 TMEM242 UBE2J1
Entrez ID		51170	127845
HPRD ID		10881	13465
Ensembl ID		ENSG00000198189	ENSG00000174567
Uniprot IDs		Q8NBQ5	Q6ZVE7
PDB IDs		1YB1
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Golgi Membrane Protein Binding Endomembrane System SNAP Receptor Activity	Membrane C-4 Methylsterol Oxidase Activity Monoacylglycerol Catabolic Process Lipid Metabolic Process Lipid Biosynthetic Process Endoplasmic Reticulum Membrane Monoacylglycerol Lipase Activity Steroid Biosynthetic Process Mitochondrial Inner Membrane Phosphatidylcholine Lysophospholipase Activity Lipid Catabolic Process Acylglycerol Catabolic Process Fatty Acid Metabolic Process Nitrate Transmembrane Transporter Activity Acyltransferase Activity Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle L-cysteine-S-conjugate N-acetyltransferase Activity Protein Binding Modified Amino Acid Metabolic Process Sterol Biosynthetic Process
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