HSD17B11

Name	hydroxysteroid 17-beta dehydrogenase 11
Structure
Interactors	54 interactors: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SERPINE1 SFRP4 SFT2D2 SFXN3 SLC25A46 SLC30A8 SLC67A1 STRIT1 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VEZT YIPF6
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Estrogen Biosynthetic Process Androgen Catabolic Process
Pathways	Estrogen biosynthesis
Drugs	Aetiocholanolone
GWAS	Appendicular lean mass ( 28724990 ) Bulimia nervosa ( 23568457 ) Lean body mass ( 28724990 )
Entrez ID	51170
HPRD ID	10881
Ensembl ID	ENSG00000198189
Uniprot IDs	Q8NBQ5
PDB IDs	1YB1
GO Terms Enriched among Interactors ?	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Golgi Membrane Protein Binding Endomembrane System SNAP Receptor Activity