GOLT1A and MGLL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GOLT1A	MGLL
Description		golgi transport 1A	monoglyceride lipase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Cis Cisterna Golgi Membrane Nuclear Envelope Cytoplasm Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Cytosol Endomembrane System Membrane	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding	Phosphatidylcholine Lysophospholipase Activity Protein Binding Hydrolase Activity Protein Homodimerization Activity Monoacylglycerol Lipase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Inflammatory Response Regulation Of Signal Transduction Lipid Catabolic Process Arachidonate Metabolic Process Triglyceride Catabolic Process Acylglycerol Catabolic Process Regulation Of Inflammatory Response Regulation Of Sensory Perception Of Pain Monoacylglycerol Catabolic Process Regulation Of Endocannabinoid Signaling Pathway
Pathways			Acyl chain remodeling of DAG and TAG Triglyceride catabolism Arachidonate production from DAG MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Carotid intima media thickness x smoking interaction ( 32117412) Femur bone mineral density x serum urate levels interaction ( 34046847) Pars triangularis volume ( 31530798) Refractive error ( 32231278)
Interacting Genes		26 interacting genes: ABHD16A AGPAT3 AQP6 C8A CCDC167 CLDND2 COX20 CPT1B FAXDC2 GPR152 GYPA HSD17B11 MGLL MSMO1 NAT8 NDUFA3 NRM OTULINL PLLP RNF24 SLC30A2 SLC35H1 TECR TIMM23 TMEM242 UBE2J1	26 interacting genes: ADRB2 AQP6 CD79A CHGB COQ9 EBAG9 FAM209A FCER1G GEM GOLT1A GPR152 HSD17B13 HTR4 LMNA LTB4R2 MSRB3 PEX12 SDCBP SLC10A6 SLC18A1 SLC66A2 SLC71A2 SLC7A14 STOM TMEM35A TMX2
Entrez ID		127845	11343
HPRD ID		13465	17574
Ensembl ID		ENSG00000174567	ENSG00000074416
Uniprot IDs		Q6ZVE7	A0A0C4DFN3 B2ZGL7 Q99685
PDB IDs			3HJU 3JW8 3JWE 3PE6 4UUQ 5ZUN 6AX1 6BQ0 7L4T 7L4U 7L4W 7L50 7PRM 7ZPG 8AQF 8PTC 8PTQ 8PTR 8RVF 9F8A 9F8B 9F8C 9F8D 9FY5
Enriched GO Terms of Interacting Partners?		Membrane C-4 Methylsterol Oxidase Activity Monoacylglycerol Catabolic Process Lipid Metabolic Process Lipid Biosynthetic Process Endoplasmic Reticulum Membrane Monoacylglycerol Lipase Activity Steroid Biosynthetic Process Mitochondrial Inner Membrane Phosphatidylcholine Lysophospholipase Activity Lipid Catabolic Process Acylglycerol Catabolic Process Fatty Acid Metabolic Process Nitrate Transmembrane Transporter Activity Acyltransferase Activity Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle L-cysteine-S-conjugate N-acetyltransferase Activity Protein Binding Modified Amino Acid Metabolic Process Sterol Biosynthetic Process
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