VPS28 and PNMA5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VPS28	PNMA5
Gene Name		vacuolar protein sorting 28 homolog (S. cerevisiae)	paraneoplastic Ma antigen family member 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	ESCRT I Complex Cytoplasm Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Complex Binding
	Biological Process	Viral Process Endosomal Transport Viral Life Cycle Virion Assembly Viral Protein Processing Negative Regulation Of Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization Intracellular Transport Of Virus	Positive Regulation Of Apoptotic Process
Pathways		Assembly Of The HIV Virion Synthesis And Processing Of GAG, GAGPOL Polyproteins HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Membrane binding and targetting of GAG proteins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: ASF1A BLZF1 CARD9 CBX5 FABP3 FAM154A GABARAP GLCCI1 GOLGA2 INCA1 MBIP PDCD6IP PNMA5 RASSF5 SKIL SMN2 TCF12 TCF4 TRIM27 TRIM54 TSG101 UBA52 USHBP1 VPS37A VPS37B VPS37C VPS52	32 interactors: AP1M1 ARPC4 C11orf49 CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 DDX6 GLIPR2 GORASP2 GRB2 KPNA2 MOAP1 MYO15B PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 TBC1D22B TNPO2 TTC23 TXNL4B VIM VPS28 WDYHV1 ZBTB25 ZFYVE26 ZMYND19
Entrez ID		51160	114824
HPRD ID		11675	06678
Ensembl ID		ENSG00000160948	ENSG00000198883
Uniprot IDs		Q548N1 Q9UK41	Q96PV4
PDB IDs
Enriched GO Terms of Interacting Partners?		Virion Assembly Viral Protein Processing Intracellular Transport Of Virus Viral Life Cycle Protein Transport Endosomal Transport Establishment Of Protein Localization Viral Process Protein Localization Membrane Organization Protein Processing Intracellular Transport Regulation Of Extracellular Vesicular Exosome Assembly Viral Budding Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Cell Cycle Establishment Of Localization In Cell Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Gene Expression Negative Regulation Of Transferase Activity Regulation Of Cell Cycle Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Cell Death Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Localization Cell Cycle Arrest Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Protein Trimerization Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Embryonic Digestive Tract Development Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Negative Regulation Of Protein Kinase Activity DNA-templated Transcription, Initiation Transport Negative Regulation Of Gene Expression Muscle Structure Development Negative Regulation Of Biosynthetic Process Negative Regulation Of Kinase Activity Cell Cycle Positive Regulation Of Lipid Biosynthetic Process Glycogen Metabolic Process	Organelle Organization Viral Process Negative Regulation Of Protein Ubiquitination Cellular Response To DNA Damage Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cell Cycle Response To Stress Cell Cycle Process Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Stress Negative Regulation Of ERBB Signaling Pathway Mitotic Cell Cycle Regulation Of Protein Ubiquitination Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Nucleotide-excision Repair, DNA Damage Recognition Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Glucose Import In Response To Insulin Stimulus Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cellular Protein Localization Positive Regulation Of Ligase Activity Regulation Of Cell Cycle Cellular Protein Catabolic Process Regulation Of ERBB Signaling Pathway Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Response To Camptothecin Protein Insertion Into Mitochondrial Membrane Regulation Of Ubiquitin-protein Transferase Activity Protein Catabolic Process Regulation Of MAPK Cascade Regulation Of Cellular Component Organization Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Nucleotide-excision Repair
Tagcloud ?		advancement cd connected counterscreen crohn encodes endosomal immortalized initiating irrespective multidomain nod2 proinflammatory regulators relapsing resource revealing reveals screen secretion sensor sorting strongest subnetworks tnfalpha usp8 validate valuable vesicle
Tagcloud (Difference) ?		advancement cd connected counterscreen crohn encodes endosomal immortalized initiating irrespective multidomain nod2 proinflammatory regulators relapsing resource revealing reveals screen secretion sensor sorting strongest subnetworks tnfalpha usp8 validate valuable vesicle
Tagcloud (Intersection) ?