VPS28 and TSNAX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VPS28	TSNAX
Description		VPS28 subunit of ESCRT-I	translin associated factor X
Image
GO Annotations	Cellular Component	ESCRT I Complex Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Membrane Late Endosome Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm Endoribonuclease Complex
	Molecular Function	Protein Binding Ubiquitin Binding Protein-containing Complex Binding	DNA Binding Single-stranded DNA Binding RNA Binding RNA Endonuclease Activity Protein Binding A2A Adenosine Receptor Binding Sequence-specific DNA Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Protein Transport Macroautophagy Negative Regulation Of Protein Ubiquitination Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Protein Catabolic Process Membrane Fission Positive Regulation Of Ubiquitin-dependent Endocytosis	Spermatogenesis Cell Differentiation SiRNA Processing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy	Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Educational attainment ( 25201988)	Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Metabolite levels ( 23823483)
Interacting Genes		48 interacting genes: ABI2 AKTIP ASF1A BEX2 BLZF1 CARD9 CBX5 CCDC146 CDK18 CEP57L1 CFTR COX5B FABP3 GABARAP GEM GLCCI1 GOLGA2 INCA1 LMO3 MBIP NRDE2 NXF1 PDCD6IP PNMA5 PRKAA2 PRKAB2 RASSF5 SAXO1 SHC3 SKIL SMN1 SMN2 SNCA SUOX TCF12 TCF4 TRIM27 TRIM54 TSG101 TSNAX UBA52 UBC USHBP1 USP2 VPS37A VPS37B VPS37C VPS52	41 interacting genes: AIMP1 AKAP9 BEX3 BLOC1S5 C1D CARD9 CDK5RAP2 CEBPA CEP68 CKAP4 COG6 EMILIN1 GADD45G GOLGA3 GPATCH2 GRIPAP1 HMGB2 KCNE4 KRT31 LDB2 LDOC1 LZTS2 MECOM MRFAP1L1 MTCL2 NSMCE2 NTAQ1 PBXIP1 PRPF18 RALYL RFC5 SPRED2 SUN1 SYCE2 SYT17 TCF12 TCP11L1 TSN TSNAXIP1 UBE2I VPS28
Entrez ID		51160	7257
HPRD ID		11675	04270
Ensembl ID		ENSG00000160948	ENSG00000116918
Uniprot IDs		A0A0S2Z5H5 Q548N1 Q9UK41	Q99598
PDB IDs		6VME	3PJA 3QB5
Enriched GO Terms of Interacting Partners?		Viral Budding Via Host ESCRT Complex Viral Budding ESCRT I Complex Multivesicular Body Organization Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Endosome Organization Macroautophagy Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Endosome Membrane Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Autophagy Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Protein Localization To Vacuole Protein Binding Vacuolar Transport Endosomal Transport Membrane Fission Multivesicular Body Sorting Pathway Cytoplasm Identical Protein Binding Ubiquitin Protein Ligase Binding Positive Regulation Of Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization To Vacuole Nucleus Viral Process Calcium-dependent Protein Binding Microtubule Binding Positive Regulation Of Exocytosis AMP-activated Protein Kinase Activity Regulation Of Extracellular Exosome Assembly Protein Transport Vesicle Organization Protein Kinase Inhibitor Activity Protein Targeting Regulation Of Protein Modification Process Nucleotide-activated Protein Kinase Complex SMN Complex Protein Targeting To Vacuole Protein-containing Complex Binding Gemini Of Cajal Bodies Positive Regulation Of Actin Nucleation Establishment Of Protein Localization Positive Regulation Of Exosomal Secretion Protein Tag Activity Organelle Assembly Establishment Of Localization In Cell Intracellular Protein Localization SMN-Sm Protein Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?