RDH11 and BLOC1S2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RDH11	BLOC1S2
Gene Name		retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	biogenesis of lysosomal organelles complex-1, subunit 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Inner Segment Intracellular Endoplasmic Reticulum Membrane Integral Component Of Membrane	Gamma-tubulin Complex Nucleus Mitochondrion Centrosome BLOC-1 Complex Recycling Endosome
	Molecular Function	Retinol Dehydrogenase Activity NADP-retinol Dehydrogenase Activity	Protein Binding Protein C-terminus Binding Gamma-tubulin Binding
	Biological Process	Retinoid Metabolic Process Phototransduction, Visible Light Adaptation Of Rhodopsin Mediated Signaling Retinol Metabolic Process Retinal Metabolic Process Oxidation-reduction Process	Microtubule Nucleation Anterograde Axon Cargo Transport Positive Regulation Of Cell Proliferation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Neuron Projection Development Melanosome Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization
Pathways		Visual phototransduction Signaling by Retinoic Acid The canonical retinoid cycle in rods (twilight vision) Diseases associated with visual transduction RA biosynthesis pathway Retinoid metabolism and transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: BLOC1S2 CA12 ROBO2	15 interactors: APP BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 FAM9B HMOX2 MEST PAM16 RDH11 SNAPIN TNNT1 WASH1
Entrez ID		51109	282991
HPRD ID		09707	12526
Ensembl ID		ENSG00000072042
Uniprot IDs		Q8TC12	F1T0F0 Q6QNY1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Negative Chemotaxis Apoptotic Process Involved In Luteolysis Regulation Of Negative Chemotaxis Luteolysis Axon Midline Choice Point Recognition Axon Choice Point Recognition Olfactory Bulb Interneuron Development Chloride Ion Homeostasis Mitochondrial Outer Membrane Permeabilization Platelet Dense Granule Organization Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Olfactory Bulb Interneuron Differentiation Negative Regulation Of Synapse Assembly Positive Regulation Of Mitochondrial Membrane Permeability Anterograde Synaptic Vesicle Transport Microtubule Nucleation Retinal Ganglion Cell Axon Guidance Melanosome Organization Pigment Granule Organization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Microtubule Polymerization Negative Regulation Of Chemotaxis Neuron Projection Development Anterograde Axon Cargo Transport Apoptotic Process Involved In Development Bicarbonate Transport Regulation Of Mitochondrial Membrane Permeability Forebrain Neuron Development Neuron Recognition Regulation Of Membrane Permeability Neuron Development Apoptotic Process Secretory Granule Organization Microtubule Polymerization Or Depolymerization Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Olfactory Bulb Development Programmed Cell Death One-carbon Metabolic Process Olfactory Lobe Development Anion Homeostasis Cell Death Death Axon Cargo Transport Neuron Differentiation Cell Projection Organization Regulation Of Synapse Assembly Cellular Pigmentation Mitochondrial Membrane Organization Forebrain Neuron Differentiation Apoptotic Mitochondrial Changes	Anterograde Synaptic Vesicle Transport Axon Cargo Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Movement Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Pigment Granule Maturation Endosome To Melanosome Transport Establishment Of Organelle Localization Intracellular Transport Cellular Pigment Accumulation Organelle Localization Microtubule-based Process Endosomal Transport Neuron Projection Development Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Neuron Development Synaptic Transmission Cellular Localization Neuron Differentiation Cell Projection Organization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Secretion Of Lysosomal Enzymes Cell-cell Signaling Secretion By Cell Developmental Pigmentation Generation Of Neurons Neurogenesis Golgi Vesicle Transport Platelet Dense Granule Organization Secretion Cell Development Positive Regulation Of Pigment Cell Differentiation Cytoplasmic Transport Transport Exocytosis
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