RDH11 and CA12

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RDH11	CA12
Gene Name		retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	carbonic anhydrase XII
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Inner Segment Intracellular Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Retinol Dehydrogenase Activity NADP-retinol Dehydrogenase Activity	Carbonate Dehydratase Activity Zinc Ion Binding
	Biological Process	Retinoid Metabolic Process Phototransduction, Visible Light Adaptation Of Rhodopsin Mediated Signaling Retinol Metabolic Process Retinal Metabolic Process Oxidation-reduction Process	One-carbon Metabolic Process Bicarbonate Transport Small Molecule Metabolic Process Chloride Ion Homeostasis
Pathways		Visual phototransduction Signaling by Retinoic Acid The canonical retinoid cycle in rods (twilight vision) Diseases associated with visual transduction RA biosynthesis pathway Retinoid metabolism and transport	Reversible hydration of carbon dioxide
Drugs			Benzthiazide Hydroflumethiazide Zonisamide Hydrochlorothiazide Ellagic Acid
Diseases
GWAS
Protein-Protein Interactions		3 interactors: BLOC1S2 CA12 ROBO2	10 interactors: ATP5C1 CUX1 DAXX KATNBL1 LGALS7 MAPK6 MRPL9 RDH11 SGSM2 TOE1
Entrez ID		51109	771
HPRD ID		09707	04464
Ensembl ID		ENSG00000072042
Uniprot IDs		Q8TC12	B3KUB4 O43570
PDB IDs			1JCZ 1JD0 4HT2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Negative Chemotaxis Apoptotic Process Involved In Luteolysis Regulation Of Negative Chemotaxis Luteolysis Axon Midline Choice Point Recognition Axon Choice Point Recognition Olfactory Bulb Interneuron Development Chloride Ion Homeostasis Mitochondrial Outer Membrane Permeabilization Platelet Dense Granule Organization Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Olfactory Bulb Interneuron Differentiation Negative Regulation Of Synapse Assembly Positive Regulation Of Mitochondrial Membrane Permeability Anterograde Synaptic Vesicle Transport Microtubule Nucleation Retinal Ganglion Cell Axon Guidance Melanosome Organization Pigment Granule Organization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Microtubule Polymerization Negative Regulation Of Chemotaxis Neuron Projection Development Anterograde Axon Cargo Transport Apoptotic Process Involved In Development Bicarbonate Transport Regulation Of Mitochondrial Membrane Permeability Forebrain Neuron Development Neuron Recognition Regulation Of Membrane Permeability Neuron Development Apoptotic Process Secretory Granule Organization Microtubule Polymerization Or Depolymerization Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Olfactory Bulb Development Programmed Cell Death One-carbon Metabolic Process Olfactory Lobe Development Anion Homeostasis Cell Death Death Axon Cargo Transport Neuron Differentiation Cell Projection Organization Regulation Of Synapse Assembly Cellular Pigmentation Mitochondrial Membrane Organization Forebrain Neuron Differentiation Apoptotic Mitochondrial Changes
Tagcloud ?			adenocarcinoma adenosquamous bilateral cea cervix chemoradiotherapy ck5 ck7 concurrent dissection distant hysterectomy intracolposcopic irregular lymphadenectomy nodes oophorectomy papillary pelvic poorer postoperative ppsc pure rarely salpingo serous unpredictable vaginal woman
Tagcloud (Difference) ?			adenocarcinoma adenosquamous bilateral cea cervix chemoradiotherapy ck5 ck7 concurrent dissection distant hysterectomy intracolposcopic irregular lymphadenectomy nodes oophorectomy papillary pelvic poorer postoperative ppsc pure rarely salpingo serous unpredictable vaginal woman
Tagcloud (Intersection) ?