ABHD5 and PLIN2

Number of citations of the paper that reports this interaction (PMID 15136565)
58

Data Source:
HPRD (two hybrid, in vitro)

		ABHD5	PLIN2
Gene Name		abhydrolase domain containing 5	perilipin 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Lipid Particle Cytosol Intracellular Membrane-bounded Organelle	Extracellular Region Nucleus Endoplasmic Reticulum Lipid Particle Cytosol Plasma Membrane
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Triglyceride Lipase Activity Lysophosphatidic Acid Acyltransferase Activity
	Biological Process	Fatty Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Negative Regulation Of Sequestering Of Triglyceride Positive Regulation Of Triglyceride Catabolic Process Triglyceride Catabolic Process Cell Differentiation Small Molecule Metabolic Process Positive Regulation Of Lipoprotein Lipase Activity	Response To Organic Cyclic Compound Long-chain Fatty Acid Transport Lipid Storage Response To Drug Cellular Lipid Metabolic Process Small Molecule Metabolic Process
Pathways		Metabolism of lipids and lipoproteins Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Lipid digestion, mobilization, and transport	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: PLIN1 PLIN2 PNPLA2	3 interactors: ABHD5 ARF1 MAPK10
Entrez ID		51099	123
HPRD ID		11986	00057
Ensembl ID			ENSG00000147872
Uniprot IDs		Q8WTS1	Q6FHZ7 Q99541
PDB IDs
Enriched GO Terms of Interacting Partners?		Triglyceride Catabolic Process Acylglycerol Catabolic Process Lipid Storage Triglyceride Metabolic Process Neutral Lipid Metabolic Process Cellular Lipid Metabolic Process Cellular Lipid Catabolic Process Lipid Metabolic Process Lipid Catabolic Process Lipid Localization Acylglycerol Acyl-chain Remodeling Glycerolipid Metabolic Process Negative Regulation Of Sequestering Of Triglyceride Small Molecule Metabolic Process Positive Regulation Of Triglyceride Catabolic Process Lipid Particle Organization Negative Regulation Of Lipid Storage Positive Regulation Of Lipid Catabolic Process Regulation Of Triglyceride Metabolic Process Long-chain Fatty Acid Transport Regulation Of Lipid Catabolic Process Regulation Of Lipid Storage Fatty Acid Transport Catabolic Process Monocarboxylic Acid Transport	Glycerophospholipid Biosynthetic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Negative Regulation Of Sequestering Of Triglyceride JUN Phosphorylation Glycerolipid Metabolic Process Phospholipid Metabolic Process Positive Regulation Of Triglyceride Catabolic Process Positive Regulation Of Lipoprotein Lipase Activity COPI Coating Of Golgi Vesicle COPI-coated Vesicle Budding Lipid Biosynthetic Process Golgi Vesicle Budding Phosphate-containing Compound Metabolic Process Negative Regulation Of Lipid Storage Long Term Synaptic Depression Cellular Copper Ion Homeostasis Regulation Of Arp2/3 Complex-mediated Actin Nucleation Triglyceride Catabolic Process Dendritic Spine Organization Copper Ion Homeostasis Regulation Of Actin Nucleation Positive Regulation Of Lipid Catabolic Process Regulation Of Defense Response To Virus By Virus Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Acylglycerol Catabolic Process Vesicle Targeting, To, From Or Within Golgi Regulation Of Receptor Internalization Regulation Of Triglyceride Metabolic Process Retrograde Vesicle-mediated Transport, Golgi To ER Cellular Lipid Metabolic Process Localization Within Membrane Vesicle Targeting Organophosphate Metabolic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Regulation Of Lipid Catabolic Process Regulation Of Lipid Storage Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Synaptic Transmission MyD88-independent Toll-like Receptor Signaling Pathway Lipid Metabolic Process Toll-like Receptor 3 Signaling Pathway Regulation Of Immune System Process MyD88-dependent Toll-like Receptor Signaling Pathway
Tagcloud ?		adenomatous aerobic ampkalpha apc attributable cgi comparative correlates crc crcs deficiency enhances falls glycolysis hydrolase intestine knockout link lipolysis lipolytic malignancies malignant mesenchymal polyps robustly shift substantially suppressing transformation	accumulate adipose aging atrogin atrophy characterizing decorated disuse donors droplets etiology hd imtg inactivity infiltration lateralis llmi mobility murf1 muscle muscular perilipins phenomenon plin5 plins sarcopenia strength triglycerides vastus
Tagcloud (Difference) ?		adenomatous aerobic ampkalpha apc attributable cgi comparative correlates crc crcs deficiency enhances falls glycolysis hydrolase intestine knockout link lipolysis lipolytic malignancies malignant mesenchymal polyps robustly shift substantially suppressing transformation	accumulate adipose aging atrogin atrophy characterizing decorated disuse donors droplets etiology hd imtg inactivity infiltration lateralis llmi mobility murf1 muscle muscular perilipins phenomenon plin5 plins sarcopenia strength triglycerides vastus
Tagcloud (Intersection) ?