PLIN2 and ABHD5

Number of citations of the paper that reports this interaction (PubMedID 15136565)
0

Data Source:
HPRD (two hybrid, in vitro)

		PLIN2	ABHD5
Description		perilipin 2	abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol Plasma Membrane Membrane	Nucleoplasm Cytoplasm Lipid Droplet Cytosol
	Molecular Function	Protein Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Triacylglycerol Lipase Activity Protein Binding Transferase Activity Acyltransferase Activity Lysophosphatidic Acid Acyltransferase Activity Carboxylic Ester Hydrolase Activity Lipase Activator Activity
	Biological Process	Response To Xenobiotic Stimulus Positive Regulation Of Triglyceride Storage Long-chain Fatty Acid Transport Lipid Storage Cellular Response To Glucose Starvation Lipid Droplet Disassembly	Lipid Metabolic Process Fatty Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process Negative Regulation Of Triglyceride Storage Positive Regulation Of Triglyceride Catabolic Process Cell Differentiation Positive Regulation Of Lipid Catabolic Process Lipid Homeostasis
Pathways		PPARA activates gene expression Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	Triglyceride catabolism
Drugs
Diseases			Dorfman-Chanarin syndrome; Chanarin-Dorfman syndrome
GWAS		Abdominal aortic calcification levels ( 31659325) Systolic blood pressure ( 30578418)	A body shape index ( 34021172) General risk tolerance (MTAG) ( 30643258) Inflammatory skin disease ( 25574825) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		9 interacting genes: ABHD5 ARF1 DESI2 HTATIP2 MAPK10 OGT POGZ SFT2D2 UBR1	21 interacting genes: CERCAM COQ8A DGAT2L6 GAD2 GET1 GRIA4 MIEF1 PCNX2 PLIN1 PLIN2 PLIN3 PNPLA2 RBFA RNF24 RUSC1 SH3GLB1 SLC44A3 TMEM14B TMEM31 TPD52L2 ZCCHC12
Entrez ID		123	51099
HPRD ID		00057	11986
Ensembl ID		ENSG00000147872	ENSG00000011198
Uniprot IDs		Q6FHZ7 Q99541	A0A0S2Z5D6 A0A2U3TZT9 C9J1D1 Q8WTS1
PDB IDs
Enriched GO Terms of Interacting Partners?			Lipid Droplet Disassembly Lipid Droplet Positive Regulation Of Triglyceride Storage Acylglycerol Acyl-chain Remodeling Lipid Storage Lipid Droplet Organization Regulation Of Lipid Storage Cellular Response To Glucose Starvation Organelle Disassembly Positive Regulation Of Lipid Storage Glycerolipid Metabolic Process ADP Binding Protein Localization To Vacuolar Membrane Cellular Response To Starvation Response To Starvation Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity
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