PLIN2 and DESI2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLIN2	DESI2
Description		perilipin 2	desumoylating isopeptidase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol Plasma Membrane Membrane	Cytoplasm
	Molecular Function	Protein Binding	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity Long-chain Fatty Acyl-CoA Hydrolase Activity K63-linked Deubiquitinase Activity Deubiquitinase Activity K48-linked Deubiquitinase Activity
	Biological Process	Response To Xenobiotic Stimulus Positive Regulation Of Triglyceride Storage Long-chain Fatty Acid Transport Lipid Storage Cellular Response To Glucose Starvation Lipid Droplet Disassembly	Proteolysis Macromolecule Depalmitoylation
Pathways		PPARA activates gene expression Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		Abdominal aortic calcification levels ( 31659325) Systolic blood pressure ( 30578418)
Interacting Genes		9 interacting genes: ABHD5 ARF1 DESI2 HTATIP2 MAPK10 OGT POGZ SFT2D2 UBR1	11 interacting genes: ARFIP1 BNIP2 COQ8A MYG1 NFU1 PBX3 PLIN2 SEMA3G SH3GLB1 SPART THAP7
Entrez ID		123	51029
HPRD ID		00057	15153
Ensembl ID		ENSG00000147872	ENSG00000121644
Uniprot IDs		Q6FHZ7 Q99541	Q9BSY9
PDB IDs
Enriched GO Terms of Interacting Partners?			Lipid Droplet Lipid Droplet Organization Cellular Response To Glucose Starvation Posterior Compartment Specification Anterior Compartment Pattern Formation Midbody Negative Regulation Of Collateral Sprouting In Absence Of Injury Negative Regulation Of Axonogenesis Negative Regulation Of Retrograde Transport, Endosome To Golgi Protein Localization To Vacuolar Membrane
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