PLIN2 and SFT2D2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		PLIN2	SFT2D2
Name		perilipin 2	SFT2 domain containing 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol Plasma Membrane Membrane	Cytoplasm Endomembrane System Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Response To Xenobiotic Stimulus Positive Regulation Of Triglyceride Storage Long-chain Fatty Acid Transport Lipid Storage Cellular Response To Glucose Starvation Lipid Droplet Disassembly	Protein Transport Vesicle-mediated Transport
Pathways		PPARA activates gene expression Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	None
GWAS		Abdominal aortic calcification levels ( 31659325 ) Systolic blood pressure ( 30578418 )	Alzheimer's disease ( 30636644 ) LDL cholesterol levels in HIV infection ( 33109212 )
Interacting Genes		9 interacting genes: ABHD5 ARF1 DESI2 HTATIP2 MAPK10 OGT POGZ SFT2D2 UBR1	29 interacting genes: AQP6 ATP5PF BNIP2 CREB3 ELOVL4 GPR152 HIBADH HSD17B11 HSD17B13 IFNGR2 INPP5K LMNA MOB2 NDRG4 PBX3 PLIN2 PLIN3 REEP2 REEP4 SLC10A1 SLC10A6 SLC30A8 STOM TAS2R5 TCP11X2 TIMM44 TMEM143 TMEM14B TMEM51
Entrez ID		123	375035
HPRD ID		00057	14192
Ensembl ID		ENSG00000147872	ENSG00000213064
Uniprot IDs		Q6FHZ7 Q99541	O95562
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Positive Regulation Of Triglyceride Storage Steroid Dehydrogenase Activity Lipid Droplet Bile Acid:sodium Symporter Activity Lipid Droplet Disassembly Endoplasmic Reticulum Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Membrane Positive Regulation Of Lipid Storage Bile Acid And Bile Salt Transport Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Nuclear Envelope Organization