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NR4A1 and NACAD
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
NR4A1
NACAD
Gene Name
nuclear receptor subfamily 4, group A, member 1
NAC alpha domain containing
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Membrane
Nucleus
Cytoplasm
Molecular Function
DNA Binding
Steroid Hormone Receptor Activity
Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Sequence-specific DNA Binding
Biological Process
Positive Regulation Of Endothelial Cell Proliferation
Cell Migration Involved In Sprouting Angiogenesis
Transcription Initiation From RNA Polymerase II Promoter
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Gene Expression
Intracellular Receptor Signaling Pathway
Endothelial Cell Chemotaxis
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Fc-epsilon Receptor Signaling Pathway
Steroid Hormone Mediated Signaling Pathway
Cellular Response To Fibroblast Growth Factor Stimulus
Innate Immune Response
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Neurotrophin TRK Receptor Signaling Pathway
Phosphatidylinositol-mediated Signaling
Protein Transport
Pathways
Signaling by the B Cell Receptor (BCR)
Signaling by FGFR in disease
PIP3 activates AKT signaling
Nuclear Receptor transcription pathway
Signaling by EGFRvIII in Cancer
Signaling by SCF-KIT
DAP12 signaling
Downstream signaling events of B Cell Receptor (BCR)
PI3K/AKT activation
Generic Transcription Pathway
PI-3K cascade
PI3K events in ERBB2 signaling
Downstream signaling of activated FGFR
Innate Immune System
Signaling by PDGF
DAP12 interactions
Signalling by NGF
GAB1 signalosome
Signaling by Ligand-Responsive EGFR Variants in Cancer
NGF signalling via TRKA from the plasma membrane
Signaling by Overexpressed Wild-Type EGFR in Cancer
Signaling by ERBB4
Constitutive PI3K/AKT Signaling in Cancer
Role of LAT2/NTAL/LAB on calcium mobilization
PI3K events in ERBB4 signaling
Signaling by FGFR
Signaling by ERBB2
Signaling by EGFR
AKT phosphorylates targets in the nucleus
Downstream signal transduction
Fc epsilon receptor (FCERI) signaling
Signaling by EGFR in Cancer
PI3K/AKT Signaling in Cancer
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
83 interactors:
ABCA5
ABCB11
ABCC13
ABCC6
ABCG8
AKT1
ANKIB1
ARHGEF10L
ARHGEF5
ATXN1
BBS10
BCL2
BCL2A1
BCL2L10
CD2AP
CDKN2D
CHD1L
CHD3
CHEK2
CPT1A
CUTA
DIABLO
EP300
FAF1
FXYD3
GADD45GIP1
GK
GLOD4
GLUD1
HADHA
HES1
HIF1A
HNRNPA2B1
HSP90AB1
KAT2B
KRTAP10-1
KRTAP10-5
LONRF1
LSS
MAP3K1
MAPK1
MAPK8
MED1
MED31
NACAD
NCOA1
NCOA2
NCOA3
NCOR2
NFKB1
NR3C1
PGBD1
PML
POLA2
PPARG
PPBP
PPM1A
PRDX4
PRDX6
RBL1
ROBO2
RPL7
RPS6KA1
RPS6KA3
RPS6KA5
RPS6KA6
RTN4
RXRG
SERPINA4
SERPING1
SMAD3
SOCS4
STAT3
SUGT1
TCF4
TP53
TRIM28
TUBB4A
VASP
VHL
YWHAZ
ZNF331
ZNF579
8 interactors:
CBLC
HDAC6
MAP4K2
NR4A1
PTK2
RPS27
TNNT1
YAE1D1
Entrez ID
3164
23148
HPRD ID
00744
Ensembl ID
ENSG00000123358
ENSG00000136274
Uniprot IDs
F5GXF0
P22736
O15069
PDB IDs
2QW4
3V3E
3V3Q
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Transcription, DNA-templated
Cellular Response To Organic Substance
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Response To Organic Substance
Regulation Of Transcription From RNA Polymerase II Promoter
Apoptotic Process
Programmed Cell Death
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Cell Death
Death
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Intrinsic Apoptotic Signaling Pathway
Cellular Response To Stress
Response To Stimulus
Intracellular Receptor Signaling Pathway
Cellular Response To Growth Factor Stimulus
DNA-templated Transcription, Initiation
Response To Growth Factor
Regulation Of Cell Death
Signal Transduction
Regulation Of Apoptotic Process
Regulation Of Signaling
Signaling
Cellular Response To Stimulus
Regulation Of Signal Transduction
Cell Communication
Apoptotic Signaling Pathway
Response To Stress
RNA Biosynthetic Process
Regulation Of Intracellular Transport
Epithelium Development
Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Gene Expression
Intracellular Signal Transduction
Regulation Of Innate Immune Response
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Placenta Development
Reproductive Structure Development
Regulation Of Metabolic Process
Reproductive System Development
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Organelle Localization
Endothelial Cell Migration
Regulation Of Catalytic Activity
Epithelial Cell Migration
Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death
Hsp90 Deacetylation
Epithelium Migration
Regulation Of Receptor Activity
Response To Growth Factor
Positive Regulation Of Chaperone-mediated Protein Complex Assembly
Polyubiquitinated Misfolded Protein Transport
Regulation Of Proteolysis
Regulation Of Epithelial Cell Migration
Regulation Of Protein Kinase Activity
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Ameboidal-type Cell Migration
Netrin-activated Signaling Pathway
Negative Regulation Of Hydrogen Peroxide Metabolic Process
Negative Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Innate Immune Response
Negative Regulation Of Cellular Protein Metabolic Process
Establishment Of Localization In Cell
Cellular Macromolecule Catabolic Process
Protein Complex Disassembly
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Synapse Assembly
Slow-twitch Skeletal Muscle Fiber Contraction
Aggresome Assembly
Tubulin Deacetylation
Positive Regulation Of Oxidative Stress-induced Cell Death
Peptidyl-lysine Deacetylation
Signal Complex Assembly
Fc Receptor Signaling Pathway
Cellular Response To Misfolded Protein
Regulation Of Protein Phosphorylation
Cellular Localization
Positive Regulation Of Receptor Biosynthetic Process
Regulation Of Hydrogen Peroxide Metabolic Process
Regulation Of MAP Kinase Activity
Cellular Protein Metabolic Process
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Response To Misfolded Protein
Establishment Of Organelle Localization
Positive Regulation Of Cellular Metabolic Process
Angiogenesis
Positive Regulation Of Cell Migration
Tagcloud
?
1alpha
adenine
afterwards
ant1
apoptotic
associate
associates
autophagy
bcl
convert
description
hypoxic
inner
latest
mim
mom
ngfib
nur77
orphan
outer
proteasomal
stabilization
summarizes
tr3
translocase
translocated
translocates
translocon
trapgamma
Tagcloud (Difference)
?
1alpha
adenine
afterwards
ant1
apoptotic
associate
associates
autophagy
bcl
convert
description
hypoxic
inner
latest
mim
mom
ngfib
nur77
orphan
outer
proteasomal
stabilization
summarizes
tr3
translocase
translocated
translocates
translocon
trapgamma
Tagcloud (Intersection)
?