SLC14A1 and TMIE

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		SLC14A1	TMIE
Name		solute carrier family 14 member 1 (Kidd blood group)	transmembrane inner ear
Structure			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane	Membrane
	Molecular Function	Water Transmembrane Transporter Activity Protein Binding Urea Transmembrane Transporter Activity Urea Channel Activity	None
	Biological Process	Water Transport Urea Transport Establishment Of Localization In Cell Transmembrane Transport Urea Transmembrane Transport	Sensory Perception Of Sound Inner Ear Morphogenesis
Pathways		SLC-mediated transport of organic cations	Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Diseases		None	Deafness, autosomal recessive
GWAS		Bladder cancer ( 21750109 21824976 ) High light scatter reticulocyte count ( 32888494 ) High light scatter reticulocyte percentage of red cells ( 32888494 ) Immature fraction of reticulocytes ( 32888494 ) Mean corpuscular hemoglobin concentration ( 29403010 ) Pursuit maintenance gain ( 29064472 ) Sum of carotid plaque area ( 32469969 ) Sum of stenosis ( 32469969 )	No GWAS studies recorded
Novel Interactors		None recorded	1 novel interactors: PBRM1
Interacting Genes		12 interacting genes: BTN2A2 C1GALT1 CFTR FIS1 GIMAP1 MIP RTP2 SNORC STRIT1 THSD7B TMEM97 TMIE	28 interacting genes: ANKRD28 AQP6 CLRN1 CREB3L1 EBP FAM210B HMOX1 JAGN1 KRT34 KRTAP10-8 KRTAP12-3 MDFI NBPF19 NOTCH2NLA PLPP6 PLPPR2 RHBDD1 SEC22A SLC14A1 SUMO1 TLCD4 TMEM101 TMEM11 TMEM14B TMEM242 TMEM51 TMPPE VAPA
Entrez ID		6563	259236
HPRD ID		00195	06252
Ensembl ID		ENSG00000141469	ENSG00000181585
Uniprot IDs		B4DFJ8 B4DHU3 F5GWS2 G0W2N5 Q13336	A0A2R8YDZ8 Q8NEW7
PDB IDs		6QD5 8BLP 8XDF	Not available
GO Terms Enriched among Interactors		Membrane Water Transport	None