BCAP31 and KLK10

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		BCAP31	KLK10
Description		B cell receptor associated protein 31	kallikrein related peptidase 10
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Plasma Membrane Membrane Clathrin-coated Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Perinuclear Endoplasmic Reticulum Lumenal Side Of Endoplasmic Reticulum Membrane	Extracellular Region Extracellular Space Secretory Granule
	Molecular Function	Protein Binding MHC Class I Protein Binding Protein-containing Complex Binding	Serine-type Endopeptidase Activity Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Protein Targeting To Mitochondrion Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Apoptotic Process Spermatogenesis Protein Transport Vesicle-mediated Transport Response To Endoplasmic Reticulum Stress Protein Localization To Endoplasmic Reticulum Exit Site Positive Regulation Of Retrograde Protein Transport, ER To Cytosol Positive Regulation Of ERAD Pathway Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Proteolysis Protein Maturation
Pathways		Apoptotic cleavage of cellular proteins Apoptotic execution phase RHOA GTPase cycle Antigen Presentation: Folding, assembly and peptide loading of class I MHC RSV-host interactions
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		30 interacting genes: ACTG1 APP AQP2 BCAP29 BCL2 BCL2L1 CANX CASP1 CASP3 CASP8 CDC42 CEBPA DRD2 FIS1 GPRIN2 HACD2 HLA-A IGHD KLK10 MSN MYH10 PLP2 SERPINF2 TIMMDC1 TMEM31 VAMP1 VAMP2 VAMP3 VKORC1 YWHAQ	2 interacting genes: BCAP31 LRIF1
Entrez ID		10134	5655
HPRD ID		02319	04054
Ensembl ID		ENSG00000185825	ENSG00000129451
Uniprot IDs		P51572	O43240 Q6ICR6
PDB IDs		4JZL 4JZP 8XWX	5LPE 5LPF
Enriched GO Terms of Interacting Partners?		Response To Peptide Response To Cytokine Regulation Of Transport SNARE Complex Assembly Response To Metal Ion Cell Projection Morphogenesis Positive Regulation Of Gene Expression Axonogenesis Neuron Projection Morphogenesis Cellular Response To Type II Interferon Membrane Positive Regulation Of Interleukin-1 Production Regulation Of Defense Response Regulation Of Neuron Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Regulation Of Inflammatory Response Regulation Of Body Fluid Levels Dendritic Cell Apoptotic Process Positive Regulation Of Inflammatory Response Membrane Organization Cellular Component Assembly Vesicle-mediated Transport Neuron Projection Positive Regulation Of Cytokine Production Response To Type II Interferon Mitochondrial Outer Membrane Regulation Of Vesicle-mediated Transport Protein-containing Complex SNAP Receptor Activity Regulation Of Immune System Process BH3 Domain Binding Response To Anesthetic Channel Activity Regulation Of Interleukin-1 Production Renal System Process Blood Microparticle Regulation Of Cytokine Production Response To Nicotine Pyroptotic Inflammatory Response Death-inducing Signaling Complex Regulation Of Histamine Secretion By Mast Cell Defense Response Cell Surface Receptor Signaling Pathway Macrophage Differentiation SNARE Complex Epithelial Cell Apoptotic Process Leukocyte Apoptotic Process Synaptic Vesicle Membrane Endocytosis Negative Regulation Of Dendritic Cell Apoptotic Process	Positive Regulation Of Anoikis Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Structural Constituent Of Eye Lens Protein Localization To Endoplasmic Reticulum Exit Site MHC Class I Protein Binding Positive Regulation Of ERAD Pathway Protein Localization To Endoplasmic Reticulum Positive Regulation Of Retrograde Protein Transport, ER To Cytosol Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Regulation Of Protein Exit From Endoplasmic Reticulum Regulation Of Retrograde Protein Transport, ER To Cytosol Perinuclear Endoplasmic Reticulum Positive Regulation Of Protein Exit From Endoplasmic Reticulum Sex-chromosome Dosage Compensation Barr Body Nuclear Retinoic Acid Receptor Binding Dosage Compensation By Inactivation Of X Chromosome Regulation Of Anoikis Regulation Of ERAD Pathway Lumenal Side Of Endoplasmic Reticulum Membrane Protein Targeting To Mitochondrion
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