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BCAP31 and SERPINF2
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
BCAP31
SERPINF2
Gene Name
B-cell receptor-associated protein 31
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Lipid Particle
Cytosol
Integral Component Of Plasma Membrane
Membrane
Clathrin-coated Vesicle
Golgi Cisterna Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
Extracellular Region
Fibrinogen Complex
Extracellular Space
Cell Surface
Platelet Alpha Granule Lumen
Extracellular Vesicular Exosome
Blood Microparticle
Molecular Function
Protein Binding
Protein Complex Binding
MHC Class I Protein Binding
Protease Binding
Endopeptidase Inhibitor Activity
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Protein Homodimerization Activity
Biological Process
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Intracellular Protein Transport
ER To Golgi Vesicle-mediated Transport
Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Positive Regulation Of Cytosolic Calcium Ion Concentration
Spermatogenesis
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Calcium-mediated Signaling Using Intracellular Calcium Source
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Protein Localization To Endoplasmic Reticulum Exit Site
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Blood Vessel Size By Renin-angiotensin
Platelet Degranulation
Acute-phase Response
Blood Coagulation
Response To Organic Substance
Negative Regulation Of Plasminogen Activation
Negative Regulation Of Endopeptidase Activity
Platelet Activation
Collagen Fibril Organization
Positive Regulation Of Collagen Biosynthetic Process
Fibrinolysis
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of JNK Cascade
Blood Vessel Morphogenesis
Positive Regulation Of Smooth Muscle Cell Proliferation
Positive Regulation Of Stress Fiber Assembly
Negative Regulation Of Fibrinolysis
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Transforming Growth Factor Beta Production
Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Pathways
Apoptotic cleavage of cellular proteins
Programmed Cell Death
Apoptotic execution phase
Class I MHC mediated antigen processing & presentation
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Adaptive Immune System
Response to elevated platelet cytosolic Ca2+
Platelet degranulation
Dissolution of Fibrin Clot
Platelet activation, signaling and aggregation
Drugs
Ocriplasmin
Diseases
GWAS
Calcium levels (
20705733
)
Serum albumin level (
23022100
)
Protein-Protein Interactions
25 interactors:
ACTG1
APP
BCAP29
BCL2
BCL2L1
CANX
CASP1
CASP3
CASP8
FIS1
GPRIN2
HACD2
HLA-A
IGHD
KLK10
LMAN1
MSN
MYH10
PLP2
SERPINF2
VAMP1
VAMP2
VAMP3
VKORC1
YWHAQ
17 interactors:
BCAP31
CFD
CTRB1
DEFA1
ELANE
F11
F13A1
FGA
KLK13
KLK2
KLK6
PLAU
PLG
PRSS1
SERPINB12
SSR1
TGM2
Entrez ID
10134
5345
HPRD ID
02319
02029
Ensembl ID
ENSG00000185825
ENSG00000167711
Uniprot IDs
P51572
P08697
PDB IDs
4JZL
4JZP
Enriched GO Terms of Interacting Partners
?
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Establishment Of Localization In Cell
Release Of Cytochrome C From Mitochondria
Regulation Of Mitochondrion Organization
Vesicle-mediated Transport
Membrane Organization
Cellular Localization
Apoptotic Process
Response To Wounding
Neuron Apoptotic Process
Immune System Process
Programmed Cell Death
Positive Regulation Of Peptidase Activity
Positive Regulation Of Mitochondrion Organization
Cell Death
Death
Neuron Death
Secretion By Cell
Apoptotic Mitochondrial Changes
Exocytosis
Apoptotic Signaling Pathway
Organelle Fusion
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Apoptotic Signaling Pathway
Intracellular Receptor Signaling Pathway
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Transport
Positive Regulation Of Cell Death
Regulation Of Endopeptidase Activity
Secretion
Immune Response
Positive Regulation Of Organelle Organization
Regulation Of Peptidase Activity
Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Establishment Of Protein Localization
Positive Regulation Of Intracellular Transport
Regulation Of Cellular Localization
Regulation Of Mitochondrial Membrane Potential
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Endoplasmic Reticulum Calcium Ion Homeostasis
Positive Regulation Of Cysteine-type Endopeptidase Activity
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Membrane Fusion
Intracellular Transport
Regulation Of Protein Localization
Positive Regulation Of Endopeptidase Activity
Extracellular Matrix Disassembly
Proteolysis
Negative Regulation Of Blood Coagulation
Negative Regulation Of Coagulation
Wound Healing
Negative Regulation Of Wound Healing
Extracellular Matrix Organization
Extracellular Structure Organization
Platelet Degranulation
Response To Wounding
Blood Coagulation
Hemostasis
Protein Metabolic Process
Regulation Of Blood Coagulation
Regulation Of Wound Healing
Regulation Of Body Fluid Levels
Positive Regulation Of Fibrinolysis
Platelet Activation
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Response To Stress
Vesicle-mediated Transport
Regulation Of Fibrinolysis
Mitochondrial Calcium Ion Homeostasis
Cobalamin Metabolic Process
Exocytosis
Killing Of Cells Of Other Organism
Defense Response To Fungus
Fibrinolysis
Protein Activation Cascade
Endoplasmic Reticulum Calcium Ion Homeostasis
Regulation Of Cell-substrate Adhesion
Response To Fungus
Secretion By Cell
Immune System Process
Peptide Cross-linking
Protein Processing
Tissue Regeneration
Positive Regulation Of Smooth Muscle Cell Proliferation
Negative Regulation Of Blood Coagulation, Common Pathway
Blood Coagulation, Common Pathway
Regulation Of Cell Adhesion
Secretion
Collagen Catabolic Process
Cellular Calcium Ion Homeostasis
Cell Activation
Calcium Ion Homeostasis
Cellular Homeostasis
Positive Regulation Of Signal Transduction
Collagen Metabolic Process
Tagcloud
?
24h
48h
anova
aureus
caprine
cd2bp2
challenged
chemotactic
cxcl6
dairy
fosl2
goats
granulocyte
halves
ilt5
infused
intramammary
intricacy
junb
lymphotoxin
mapk13
mastitis
mhcii
microarrays
mscs
pbs
udder
udders
veterinary
Tagcloud (Difference)
?
24h
48h
anova
aureus
caprine
cd2bp2
challenged
chemotactic
cxcl6
dairy
fosl2
goats
granulocyte
halves
ilt5
infused
intramammary
intricacy
junb
lymphotoxin
mapk13
mastitis
mhcii
microarrays
mscs
pbs
udder
udders
veterinary
Tagcloud (Intersection)
?