TRAT1 and TRB

Number of citations of the paper that reports this interaction (PMID 11390434)
17

Data Source:
HPRD (in vivo)

		TRAT1	TRB
Gene Name		T cell receptor associated transmembrane adaptor 1	T cell receptor beta locus
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane T Cell Receptor Complex
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
	Biological Process	Negative Regulation Of Receptor Recycling Cellular Defense Response Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Positive Regulation Of Calcium-mediated Signaling T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of Transport
Pathways		Signaling by the B Cell Receptor (BCR) Downstream TCR signaling Signaling by FGFR in disease PIP3 activates AKT signaling Signaling by EGFRvIII in Cancer Signaling by SCF-KIT Downstream signaling events of B Cell Receptor (BCR) DAP12 signaling PI3K/AKT activation PI-3K cascade PI3K events in ERBB2 signaling Downstream signaling of activated FGFR Innate Immune System Signaling by PDGF Signalling by NGF DAP12 interactions GAB1 signalosome Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane Signaling by ERBB4 Signaling by Overexpressed Wild-Type EGFR in Cancer Role of LAT2/NTAL/LAB on calcium mobilization Constitutive PI3K/AKT Signaling in Cancer PI3K events in ERBB4 signaling Signaling by FGFR Signaling by ERBB2 Signaling by EGFR TCR signaling Downstream signal transduction Fc epsilon receptor (FCERI) signaling Signaling by EGFR in Cancer PI3K/AKT Signaling in Cancer Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CD247 CD3E FYN GRB2 LCK LCP2 LYN PIK3R1 SRC TRA TRB	15 interactors: CD1D CD247 CD3D CD3E CD3G CTCF HLA-A HLA-B HLA-DRB1 NCOA6 NCOR1 TAF1B TRA TRAT1 TRD
Entrez ID		50852	6957
HPRD ID		05392	01739
Ensembl ID		ENSG00000163519
Uniprot IDs		Q6PIZ9
PDB IDs
Enriched GO Terms of Interacting Partners?		T Cell Costimulation Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Immune Response-regulating Signaling Pathway Positive Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Cell Activation Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune Response Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Platelet Activation Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Cell Activation T Cell Receptor Signaling Pathway Regulation Of Cell Adhesion Cell Activation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Immune System Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Innate Immune Response Blood Coagulation Hemostasis Enzyme Linked Receptor Protein Signaling Pathway Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Viral Process Phagocytosis Regulation Of Body Fluid Levels Wound Healing Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Immune System Process Response To Wounding Immune Response Peptidyl-tyrosine Autophosphorylation Defense Response Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Peptide Hormone Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor	Positive Regulation Of Immune Response Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion T Cell Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion Antigen Receptor-mediated Signaling Pathway Regulation Of Immune Response Regulation Of T Cell Activation Positive Regulation Of Cell Activation Positive Regulation Of Immune System Process Detection Of Bacterium T Cell Costimulation Immune System Process Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Detection Of Biotic Stimulus Regulation Of Cell Activation Regulation Of Immune System Process Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Antigen Processing And Presentation Of Endogenous Antigen Innate Immune Response Immune Response-regulating Signaling Pathway T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Protection From Natural Killer Cell Mediated Cytotoxicity T Cell Differentiation Immune Response T Cell Selection Lymphocyte Activation Defense Response Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Leukocyte Activation Cell Surface Receptor Signaling Pathway Single Organismal Cell-cell Adhesion Antigen Processing And Presentation Lymphocyte Differentiation Interferon-gamma-mediated Signaling Pathway Regulation Of T Cell Anergy Regulation Of Interferon-gamma Production Hemopoiesis Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Cellular Response To Interferon-gamma
Tagcloud ?			cdr3 clonotypes complementarity detailed effusion expansive extrapulmonary families firstly illumina manifestation mononuclear oligoclonal pbmcs peaks pemcs platform pleural pltb profiled repertoire sequenced skewed spectratyping tcr throughput trbj1 trbv trbv20
Tagcloud (Difference) ?			cdr3 clonotypes complementarity detailed effusion expansive extrapulmonary families firstly illumina manifestation mononuclear oligoclonal pbmcs peaks pemcs platform pleural pltb profiled repertoire sequenced skewed spectratyping tcr throughput trbj1 trbv trbv20
Tagcloud (Intersection) ?