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TRAT1
Gene Name
T cell receptor associated transmembrane adaptor 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
T Cell Receptor Complex
Molecular Function
Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
Biological Process
Negative Regulation Of Receptor Recycling
Cellular Defense Response
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Innate Immune Response
Neurotrophin TRK Receptor Signaling Pathway
Phosphatidylinositol-mediated Signaling
Positive Regulation Of Calcium-mediated Signaling
T Cell Receptor Signaling Pathway
Positive Regulation Of T Cell Receptor Signaling Pathway
Negative Regulation Of Transport
Pathways
Signaling by the B Cell Receptor (BCR)
Downstream TCR signaling
Signaling by FGFR in disease
PIP3 activates AKT signaling
Signaling by EGFRvIII in Cancer
Signaling by SCF-KIT
Downstream signaling events of B Cell Receptor (BCR)
DAP12 signaling
PI3K/AKT activation
PI-3K cascade
PI3K events in ERBB2 signaling
Downstream signaling of activated FGFR
Innate Immune System
Signaling by PDGF
Signalling by NGF
DAP12 interactions
GAB1 signalosome
Signaling by Ligand-Responsive EGFR Variants in Cancer
NGF signalling via TRKA from the plasma membrane
Signaling by ERBB4
Signaling by Overexpressed Wild-Type EGFR in Cancer
Role of LAT2/NTAL/LAB on calcium mobilization
Constitutive PI3K/AKT Signaling in Cancer
PI3K events in ERBB4 signaling
Signaling by FGFR
Signaling by ERBB2
Signaling by EGFR
TCR signaling
Downstream signal transduction
Fc epsilon receptor (FCERI) signaling
Signaling by EGFR in Cancer
PI3K/AKT Signaling in Cancer
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions
11 interactors:
CD247
CD3E
FYN
GRB2
LCK
LCP2
LYN
PIK3R1
SRC
TRA
TRB
Entrez ID
50852
HPRD ID
05392
Ensembl ID
ENSG00000163519
Uniprot IDs
Q6PIZ9
PDB IDs
Enriched GO Terms of Interacting Partners
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T Cell Costimulation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Immune Response-regulating Signaling Pathway
Positive Regulation Of Cell-cell Adhesion
Fc Receptor Signaling Pathway
Regulation Of T Cell Activation
Positive Regulation Of Cell Activation
Antigen Receptor-mediated Signaling Pathway
Positive Regulation Of Immune Response
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Regulation Of Lymphocyte Activation
Platelet Activation
Regulation Of Immune Response
Positive Regulation Of Immune System Process
Regulation Of Cell Activation
T Cell Receptor Signaling Pathway
Regulation Of Cell Adhesion
Cell Activation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Immune System Process
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Innate Immune Response
Blood Coagulation
Hemostasis
Enzyme Linked Receptor Protein Signaling Pathway
Leukocyte Migration
Fc-epsilon Receptor Signaling Pathway
Viral Process
Phagocytosis
Regulation Of Body Fluid Levels
Wound Healing
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Immune System Process
Response To Wounding
Immune Response
Peptidyl-tyrosine Autophosphorylation
Defense Response
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Response To Peptide Hormone
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
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