PDCL and CCT5

Number of citations of the paper that reports this interaction (PMID 15889144)
25

Data Source:
HPRD (in vivo)

		PDCL	CCT5
Gene Name		phosducin-like	chaperonin containing TCP1, subunit 5 (epsilon)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Zona Pellucida Receptor Complex Nucleolus Cytoplasm Centrosome Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Vesicular Exosome
	Molecular Function	Receptor Signaling Protein Activity Protein Binding Protein Complex Binding	Protein Binding ATP Binding G-protein Beta-subunit Binding Beta-tubulin Binding Unfolded Protein Binding
	Biological Process	Protein Folding Signal Transduction Visual Perception Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Intracellular Signal Transduction Negative Regulation Of Protein Refolding Heterotrimeric G-protein Complex Assembly	Protein Folding Binding Of Sperm To Zona Pellucida Response To Virus Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Toxin Transport
Pathways			Cargo trafficking to the periciliary membrane Protein folding Organelle biogenesis and maintenance Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Association of TriC/CCT with target proteins during biosynthesis Chaperonin-mediated protein folding Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Pain ( 22956598)
Protein-Protein Interactions		7 interactors: ADRBK1 CCT5 EIF3I GNB1 IKBKG PSMC5 TCP1	15 interactors: ACTA1 ACTA2 ACTB HDAC3 IKBKAP IMMT PDCL SSSCA1 SUMO4 TBC1D17 TCP1 TERT THEG TP53 XRN1
Entrez ID		5082	22948
HPRD ID		05108	06468
Ensembl ID		ENSG00000136940	ENSG00000150753
Uniprot IDs		Q13371	B4DYD8 B7ZAR1 E7ENZ3 E9PCA1 P48643
PDB IDs
Enriched GO Terms of Interacting Partners?		G-protein Coupled Acetylcholine Receptor Signaling Pathway Toxin Transport Binding Of Sperm To Zona Pellucida Sperm-egg Recognition 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Cell-cell Recognition Negative Regulation Of The Force Of Heart Contraction By Chemical Signal Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm Cell Recognition Single Fertilization Fertilization Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Inclusion Body Assembly Cardiac Muscle Cell Apoptotic Process Apoptotic Process Negative Regulation Of Striated Muscle Contraction Muscle Cell Apoptotic Process Programmed Cell Death Response To Virus Regulation Of The Force Of Heart Contraction By Chemical Signal Cell Death Death Tachykinin Receptor Signaling Pathway Cellular Metabolic Process Negative Regulation Of Signal Transduction Protein Folding Cellular Protein Metabolic Process Positive Regulation Of Catecholamine Secretion Regulation Of Macrophage Apoptotic Process Negative Regulation Of Signaling Tubulin Complex Assembly Cellular Response To Prostaglandin E Stimulus Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Regulation Of Inclusion Body Assembly Regulation Of Signal Transduction Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway	Cellular Component Assembly Protein Complex Assembly Replicative Senescence Chromatin Organization Chromosome Organization 'de Novo' Posttranslational Protein Folding Heterotrimeric G-protein Complex Assembly Negative Regulation Of Production Of SiRNA Involved In RNA Interference Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm 'de Novo' Protein Folding Protein Folding Cell Aging Negative Regulation Of Macromitophagy Negative Regulation Of RNA Interference Skeletal Muscle Fiber Adaptation Transcription, RNA-templated Oligodendrocyte Apoptotic Process Organelle Organization Negative Regulation Of Helicase Activity Telomere Formation Via Telomerase Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Negative Regulation Of Protein Refolding Notch Signaling Pathway Positive Regulation Of Thymocyte Apoptotic Process Glomerular Mesangial Cell Development Positive Regulation Of Cell Aging Skeletal Muscle Thin Filament Assembly Mitochondrial DNA Repair Mesangial Cell Development Telomere Assembly Nuclear MRNA Surveillance Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Renal Interstitial Fibroblast Development Glial Cell Apoptotic Process Circadian Rhythm Skeletal Myofibril Assembly Oxidative Stress-induced Premature Senescence RNA Surveillance
Tagcloud ?		2h2o 4h2o adp adriamycin anticancer antigrowth bax chemotherapeutics cisplatin complexes elucidate far fluorescein iodide isothiocyanate jurkat molt mtt palladium predominately propidium regarded ribose sac satisfactory terpy thp treating warranted	cd68 ddx5 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
Tagcloud (Difference) ?		2h2o 4h2o adp adriamycin anticancer antigrowth bax chemotherapeutics cisplatin complexes elucidate far fluorescein iodide isothiocyanate jurkat molt mtt palladium predominately propidium regarded ribose sac satisfactory terpy thp treating warranted	cd68 ddx5 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
Tagcloud (Intersection) ?