PAK2 and RAC1

  • Number of citations of the paper that reports this interaction (PMID 20936779)
  • 48
  • Data Source:
  • BioGRID (two hybrid, pull down)
  • HPRD (in vitro)

PAK2

RAC1

Gene Name p21 protein (Cdc42/Rac)-activated kinase 2 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 51 interactors: ABI1 ABI3 ABL1 APP ARHGAP10 ARHGEF6 ARHGEF7 BRAF CASP3 CDC42 DOCK2 DST EIF4B EIF4G1 EP300 FYN GRB2 HCK HIST1H4F LCK LIMK1 LYN MAPK1 MAPK3 MKNK1 MYC MYL2 MYLK NCK1 NPHP1 PACSIN3 RAC1 RAC2 RAF1 RHOJ RIOK3 RPS6 SH3GL2 SH3KBP1 SH3PXD2A SH3RF1 SH3RF3 SNX33 SNX9 SORBS1 SORBS2 SORBS3 SRC SYN1 VIM YES1 144 interactors: ACTA1 ACTB AKT1 ARFIP2 ARHGAP1 ARHGAP15 ARHGAP17 ARHGAP27 ARHGAP31 ARHGAP32 ARHGAP33 ARHGAP44 ARHGDIA ARHGDIB ARHGDIG ARHGEF2 ARHGEF25 ARHGEF4 ARHGEF7 ARL2BP BAG6 BAIAP2 BCR BIRC2 BRINP1 CASP3 CASP7 CAV1 CDC23 CDC42 CDC42BPG CDC42SE1 CDC42SE2 CFAP36 CHN1 CHN2 CIT CNTNAP1 COG5 COX3 CSN2 CYBA CYBB CYFIP1 DEF6 DIAPH1 DIAPH3 DMPK DOCK1 DOCK2 DOCK8 DVL1 DVL2 EIF2AK2 FHOD1 FLNA FMNL1 GRN HACD3 HPS4 ICMT IFNGR1 IL1RAP IQGAP1 IQGAP2 KALRN KPNA4 KPNA6 KRT40 KTN1 LATS1 LTBP3 LTBP4 LZTS2 MAGI1 MAP3K10 MAP3K11 MAP3K4 MCF2L MCM3AP METAP2 MTNR1A MYD88 MYH9 NCF2 NCK1 NCKAP1 NEDD4 NME1 NOS2 NOXA1 OCRL OPHN1 PAK1 PAK2 PAK3 PAK7 PARD6A PARD6B PARD6G PARK2 PIAS3 PIK3R1 PIP4K2A PLD1 PLEKHG2 PLXNB1 PPP2R2B PRKCA PRKCD PRKCI PRMT6 PTK2 RALBP1 RAP1GDS1 RASGRF1 RCC2 RGL2 RPS6KB1 SET SFPQ SH3BP1 SH3RF1 SH3RF3 STAT1 STAT3 STAU1 SUMO2 SYNJ2 TBC1D3F TIAM1 TLR2 TNFRSF12A TRIO TUBA4A UNKL USH1C USP6 VAV1 VAV2 VAV3 VWF WAS WASF1
Entrez ID 5062 5879
HPRD ID 05428 03627
Ensembl ID ENSG00000180370 ENSG00000136238
Uniprot IDs A8K5M4 Q13177 A4D2P0 A4D2P1 P63000
PDB IDs 3PCS 1E96 1FOE 1G4U 1HE1 1HH4 1I4D 1I4L 1I4T 1MH1 1RYF 1RYH 2FJU 2H7V 2NZ8 2P2L 2RMK 2VRW 2WKP 2WKQ 2WKR 2YIN 3B13 3BJI 3RYT 3SBD 3SBE 3SU8 3SUA 3TH5 4GZL 4GZM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
cot  densitometry  erk2  hog  immunoreactivities  jnks  kinases  mapkapk2  mapks  mek1  mekkl  mkk3  mlk3  mos  myocytes  pakl  phenomena  probed  proliferate  proto  raf1  rafb  resist  rsk1  rsk2  sekl  tpl  ventricle  ventricles 
3t3  activate  bind  chimeric  cytoskeletal  dispensable  effector  effectors  interrelationship  jnk  jun  lamellipodia  lamellipodium  mediate  nh2  nih  p65  pak  ras  rho  rhoa  ruffling  srf  stimulate  surprisingly  threonine  transformation  transforming  tumorigenic 
Tagcloud (Difference) ?
cot  densitometry  erk2  hog  immunoreactivities  jnks  kinases  mapkapk2  mapks  mek1  mekkl  mkk3  mlk3  mos  myocytes  pakl  phenomena  probed  proliferate  proto  raf1  rafb  resist  rsk1  rsk2  sekl  tpl  ventricle  ventricles 
3t3  activate  bind  chimeric  cytoskeletal  dispensable  effector  effectors  interrelationship  jnk  jun  lamellipodia  lamellipodium  mediate  nh2  nih  p65  pak  ras  rho  rhoa  ruffling  srf  stimulate  surprisingly  threonine  transformation  transforming  tumorigenic 
Tagcloud (Intersection) ?