RAC1 and DOCK1

  • Number of citations of the paper that reports this interaction (PMID 12134158)
  • 109
  • Data Source:
  • BioGRID (pull down)
  • HPRD (in vitro, in vivo)

RAC1

DOCK1

Gene Name ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) dedicator of cytokinesis 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 144 interactors: ACTA1 ACTB AKT1 ARFIP2 ARHGAP1 ARHGAP15 ARHGAP17 ARHGAP27 ARHGAP31 ARHGAP32 ARHGAP33 ARHGAP44 ARHGDIA ARHGDIB ARHGDIG ARHGEF2 ARHGEF25 ARHGEF4 ARHGEF7 ARL2BP BAG6 BAIAP2 BCR BIRC2 BRINP1 CASP3 CASP7 CAV1 CDC23 CDC42 CDC42BPG CDC42SE1 CDC42SE2 CFAP36 CHN1 CHN2 CIT CNTNAP1 COG5 COX3 CSN2 CYBA CYBB CYFIP1 DEF6 DIAPH1 DIAPH3 DMPK DOCK1 DOCK2 DOCK8 DVL1 DVL2 EIF2AK2 FHOD1 FLNA FMNL1 GRN HACD3 HPS4 ICMT IFNGR1 IL1RAP IQGAP1 IQGAP2 KALRN KPNA4 KPNA6 KRT40 KTN1 LATS1 LTBP3 LTBP4 LZTS2 MAGI1 MAP3K10 MAP3K11 MAP3K4 MCF2L MCM3AP METAP2 MTNR1A MYD88 MYH9 NCF2 NCK1 NCKAP1 NEDD4 NME1 NOS2 NOXA1 OCRL OPHN1 PAK1 PAK2 PAK3 PAK7 PARD6A PARD6B PARD6G PARK2 PIAS3 PIK3R1 PIP4K2A PLD1 PLEKHG2 PLXNB1 PPP2R2B PRKCA PRKCD PRKCI PRMT6 PTK2 RALBP1 RAP1GDS1 RASGRF1 RCC2 RGL2 RPS6KB1 SET SFPQ SH3BP1 SH3RF1 SH3RF3 STAT1 STAT3 STAU1 SUMO2 SYNJ2 TBC1D3F TIAM1 TLR2 TNFRSF12A TRIO TUBA4A UNKL USH1C USP6 VAV1 VAV2 VAV3 VWF WAS WASF1 8 interactors: BCAR1 CRK ELMO1 ELMO2 NCK2 RAC1 RHOG WASF2
Entrez ID 5879 1793
HPRD ID 03627 03240
Ensembl ID ENSG00000136238 ENSG00000150760
Uniprot IDs A4D2P0 A4D2P1 P63000 Q14185
PDB IDs 1E96 1FOE 1G4U 1HE1 1HH4 1I4D 1I4L 1I4T 1MH1 1RYF 1RYH 2FJU 2H7V 2NZ8 2P2L 2RMK 2VRW 2WKP 2WKQ 2WKR 2YIN 3B13 3BJI 3RYT 3SBD 3SBE 3SU8 3SUA 3TH5 4GZL 4GZM 3L4C
Enriched GO Terms of Interacting Partners?
Tagcloud ?
3t3  activate  bind  chimeric  cytoskeletal  dispensable  effector  effectors  interrelationship  jnk  jun  lamellipodia  lamellipodium  mediate  nh2  nih  p65  pak  ras  rho  rhoa  ruffling  srf  stimulate  surprisingly  threonine  transformation  transforming  tumorigenic 
adhesion  adhesions  cadherin  canine  completion  contacts  coordinate  coordination  darby  dynamic  elmo  elmo2  exchange  gtpase  guanine  integrin  interference  localize  madin  rac  recruits  reorganization  requiring  rho  screen  spreading  subsequently  unexpected 
Tagcloud (Difference) ?
3t3  activate  bind  chimeric  cytoskeletal  dispensable  effector  effectors  interrelationship  jnk  jun  lamellipodia  lamellipodium  mediate  nh2  nih  p65  pak  ras  rhoa  ruffling  srf  stimulate  surprisingly  threonine  transformation  transforming  tumorigenic 
adhesion  adhesions  cadherin  canine  completion  contacts  coordinate  coordination  darby  dynamic  elmo  elmo2  exchange  gtpase  guanine  integrin  interference  localize  madin  rac  recruits  reorganization  requiring  screen  spreading  subsequently  unexpected 
Tagcloud (Intersection) ?
rho