ORC5 and TXNDC11

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ORC5	TXNDC11
Gene Name		origin recognition complex, subunit 5	thioredoxin domain containing 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Origin Recognition Complex Nucleus Nucleoplasm Nuclear Origin Of Replication Recognition Complex Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Nucleotide Binding Molecular_function DNA Replication Origin Binding Protein Binding ATP Binding	Protein Disulfide Isomerase Activity Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Replication DNA Replication Initiation	Protein Folding Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis
Pathways		G2/M Checkpoints Activation of the pre-replicative complex Activation of the pre-replicative complex Orc1 removal from chromatin Assembly of the pre-replicative complex Activation of ATR in response to replication stress G1/S Transition Assembly of the ORC complex at the origin of replication Removal of licensing factors from origins Mitotic G1-G1/S phases Switching of origins to a post-replicative state E2F mediated regulation of DNA replication Synthesis of DNA DNA Replication Pre-Initiation Regulation of DNA replication M/G1 Transition S Phase CDC6 association with the ORC:origin complex Cell Cycle, Mitotic Orc1 removal from chromatin E2F-enabled inhibition of pre-replication complex formation Cell Cycle Checkpoints Association of licensing factors with the pre-replicative complex CDT1 association with the CDC6:ORC:origin complex
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: CALCOCO2 CDC45 CDC5L CDC6 CDC7 DBF4 DMRTA1 HIST3H3 HIST4H4 KRT18 LAMB2 MCM2 MCM3 MCM4 MCM5 MCM7 NIF3L1 NONO ORC1 ORC2 ORC3 ORC4 ORC6 RPA2 SIPA1L2 STAB1 TAX1BP1 TXNDC11 UBQLN4	17 interactors: ACAA1 ATXN7 CDKN1A DUOX1 DUOX2 GFI1B HSP90B1 KRT15 KRT18 NOS3 ORC5 RACGAP1 RPS19 RPS6KA5 SOCS3 STAT5A TPO
Entrez ID		5001	51061
HPRD ID		09086	07125
Ensembl ID		ENSG00000164815	ENSG00000153066
Uniprot IDs		A4D0P7 O43913 Q53FC8	Q6PKC3
PDB IDs
Enriched GO Terms of Interacting Partners?		G1/S Transition Of Mitotic Cell Cycle DNA Replication Initiation Mitotic Cell Cycle Phase Transition DNA Replication Cell Cycle Phase Transition DNA-dependent DNA Replication DNA Metabolic Process Mitotic Cell Cycle Mitotic Cell Cycle Process Cell Cycle DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Cell Cycle Process DNA Duplex Unwinding DNA Geometric Change Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process DNA Conformation Change Biosynthetic Process DNA Unwinding Involved In DNA Replication Double-strand Break Repair Via Break-induced Replication Chromosome Organization Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Protein-DNA Complex Assembly Positive Regulation Of Cell Cycle Phase Transition Cellular Response To Stress Cellular Response To DNA Damage Stimulus DNA Replication Checkpoint Telomere Maintenance Double-strand Break Repair Via Homologous Recombination Recombinational Repair Regulation Of Mitotic Cell Cycle Phase Transition Cell Cycle Checkpoint DNA Recombination Cellular Metabolic Process Regulation Of Cell Cycle Process Response To Stress Nuclear DNA Replication Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Epidermal Growth Factor Stimulus Regulation Of G1/S Transition Of Mitotic Cell Cycle	Thyroid Hormone Generation Hydrogen Peroxide Catabolic Process Thyroid Hormone Metabolic Process Cytokine-mediated Signaling Pathway Regulation Of Innate Immune Response Reactive Oxygen Species Metabolic Process Anatomical Structure Development Cuticle Development Cellular Response To Organic Substance Hydrogen Peroxide Metabolic Process Cellular Response To Cytokine Stimulus Developmental Process Immune System Process Response To Cytokine Hormone Biosynthetic Process Positive Regulation Of Innate Immune Response Response To Organonitrogen Compound Response To Organic Substance Regulation Of Immune Response Cellular Modified Amino Acid Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Phenol-containing Compound Metabolic Process Negative Regulation Of Cell Death Multicellular Organismal Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Catabolic Process Growth Hormone Receptor Signaling Pathway System Development Response To Organophosphorus Cellular Response To Growth Hormone Stimulus Regulation Of Immune System Process Response To Stress Response To Purine-containing Compound Hormone Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Response To Growth Hormone Regulation Of Protein Metabolic Process Regulation Of Cell Death Organ Development JAK-STAT Cascade Cell Surface Receptor Signaling Pathway Organelle Organization Histone H2A-S1 Phosphorylation Cytokinesis, Initiation Of Separation Actomyosin Contractile Ring Assembly
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?