ANKRD2 and ZBTB3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		ANKRD2	ZBTB3
Description		ankyrin repeat domain 2	zinc finger and BTB domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Euchromatin Nucleus Cytoplasm Cytosol PML Body I Band	Nucleus
	Molecular Function	Protein Binding Structural Constituent Of Muscle Protein Kinase B Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Muscle Contraction Muscle Organ Development Regulation Of Gene Expression Negative Regulation Of Myoblast Differentiation	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: FCMR HBP1 HOMEZ LDB3 MAPK6 PML TCAP TP53 TTN YBX1 ZBTB3	24 interacting genes: ANKRD2 AP1M1 BIN1 EIF5B FOXM1 GATA4 GTF2A1L IKBKG IRF6 JADE2 LEF1 MYO15B NR3C1 PKNOX1 PPARG PROX1 SKIL SMAD3 SMYD1 SSX3 SUPT5H THRA ZMYM2 ZNF556
Entrez ID		26287	79842
HPRD ID		12460	15693
Ensembl ID		ENSG00000165887	ENSG00000185670
Uniprot IDs		A0A0A0MRN9 Q5T457 Q9GZV1	A0A6E1W9L1
PDB IDs
Enriched GO Terms of Interacting Partners?		Titin-telethonin Complex Sarcomerogenesis Skeletal Muscle Myosin Thick Filament Assembly Myosin Filament Assembly Sarcomere Organization Skeletal Muscle Thin Filament Assembly Detection Of Muscle Stretch Muscle Alpha-actinin Binding Cardiac Myofibril Assembly Muscle Filament Sliding Actomyosin Structure Organization Actin-myosin Filament Sliding Negative Regulation Of Telomere Maintenance Via Telomerase Z Disc Entrainment Of Circadian Clock By Photoperiod Cardiac Muscle Hypertrophy Response To Muscle Stretch I Band Photoperiodism Entrainment Of Circadian Clock Muscle Hypertrophy Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Myofibril Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Skeletal Muscle Contraction Negative Regulation Of Telomere Maintenance Actin-mediated Cell Contraction Cardiac Muscle Cell Development Regulation Of Telomere Maintenance Via Telomerase Structural Constituent Of Muscle Cardiac Muscle Contraction Cardiac Cell Development Detection Of Mechanical Stimulus Somitogenesis DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cellular Senescence Regulation Of Telomere Maintenance Via Telomere Lengthening Response To Gamma Radiation Segmentation Negative Regulation Of Translation In Response To Oxidative Stress Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Heart Development Cardiac Muscle Tissue Morphogenesis High-affinity IgM Receptor Activity Actin Filament-based Movement Cellular Senescence	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Negative Regulation Of RNA Biosynthetic Process Sequence-specific DNA Binding Negative Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Transcription Cis-regulatory Region Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Activity Positive Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Nucleus Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin DNA Binding Epithelial Cell Differentiation Animal Organ Development Negative Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription By RNA Polymerase II Negative Regulation Of Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process DNA Binding Domain Binding Positive Regulation Of Biosynthetic Process DNA-templated Transcription Myeloid Cell Differentiation Cell Differentiation DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Regulator Complex Gland Development Transdifferentiation LBD Domain Binding Chromatin Binding Tube Morphogenesis
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