ANKRD2 and FAIM3

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		ANKRD2	FAIM3
Gene Name		ankyrin repeat domain 2 (stretch responsive muscle)	Fas apoptotic inhibitory molecule 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Euchromatin Nucleus Cytosol PML Body Sarcomere I Band Intracellular Membrane-bounded Organelle	Extracellular Region Integral Component Of Membrane
	Molecular Function	Structural Constituent Of Muscle Titin Binding Protein Kinase B Binding RNA Polymerase II Sequence-specific DNA Binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Muscle Contraction Muscle Organ Development Skeletal Muscle Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Myoblast Differentiation	Immune System Process Cellular Defense Response Negative Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		8 interactors: FAIM3 HBP1 PML TCAP TP53 TTN YBX1 ZBTB3	3 interactors: ANKRD2 HOXD9 ZNHIT3
Entrez ID		26287	9214
HPRD ID		12460	09349
Ensembl ID		ENSG00000165887
Uniprot IDs		Q9GZV1	O60667
PDB IDs
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Myosin Thick Filament Assembly Sarcomerogenesis Detection Of Muscle Stretch Myosin Filament Assembly Skeletal Muscle Thin Filament Assembly Skeletal Myofibril Assembly Cardiac Muscle Fiber Development Response To Muscle Stretch Cell Cycle Arrest Adult Heart Development Protein Import Positive Regulation Of Histone Deacetylation Cardiac Myofibril Assembly Entrainment Of Circadian Clock By Photoperiod Positive Regulation Of Protein Deacetylation Cardiac Muscle Hypertrophy Photoperiodism Entrainment Of Circadian Clock Muscle Hypertrophy Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Cellular Senescence Actin-myosin Filament Sliding Muscle Filament Sliding Regulation Of Histone Deacetylation Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Actin-mediated Cell Contraction Negative Regulation Of DNA Replication Detection Of Mechanical Stimulus Regulation Of Protein Deacetylation Muscle Fiber Development Response To Gamma Radiation Cardiac Muscle Contraction Sarcomere Organization DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Cardiac Muscle Tissue Morphogenesis Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Actin Filament-based Movement Muscle Tissue Morphogenesis Regulation Of Tissue Remodeling Heart Contraction Protein Complex Assembly Cell Cycle Process Cardiac Muscle Cell Development Muscle Organ Morphogenesis Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint	Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Muscle Organ Development Striated Muscle Tissue Development Muscle Tissue Development Muscle Structure Development Peripheral Nervous System Neuron Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Myoblast Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Myoblast Differentiation Negative Regulation Of Muscle Cell Differentiation Proximal/distal Pattern Formation Regulation Of Transcription, DNA-templated Embryonic Forelimb Morphogenesis Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Forelimb Morphogenesis Skeletal Muscle Cell Differentiation Hindlimb Morphogenesis Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Peripheral Nervous System Development Adult Locomotory Behavior Tissue Development Embryonic Skeletal System Morphogenesis Single Fertilization Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		a165v a171t actinin2 alternatively cardiomyopathy compaction competition cypher cytoskeletal differs dilated homologue indication lethality lim mechanosensing motif multiprotein myofibrillar myopathy nomenclature pdz sarcomeres spliced striated sumoylation zasp zaspopathy zm
Tagcloud (Difference) ?		a165v a171t actinin2 alternatively cardiomyopathy compaction competition cypher cytoskeletal differs dilated homologue indication lethality lim mechanosensing motif multiprotein myofibrillar myopathy nomenclature pdz sarcomeres spliced striated sumoylation zasp zaspopathy zm
Tagcloud (Intersection) ?