ANKRD2 and FCMR

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		ANKRD2	FCMR
Description		ankyrin repeat domain 2	Fc mu receptor
Image		No pdb structure
GO Annotations	Cellular Component	Euchromatin Nucleus Cytoplasm Cytosol PML Body I Band	Extracellular Region Nucleoplasm Lysosome Lysosomal Membrane Endosome Golgi Apparatus Centrosome Plasma Membrane Membrane Early Endosome Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Structural Constituent Of Muscle Protein Kinase B Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Polymeric Immunoglobulin Binding IgM Binding High-affinity IgM Receptor Activity Transmembrane Signaling Receptor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Muscle Contraction Muscle Organ Development Regulation Of Gene Expression Negative Regulation Of Myoblast Differentiation	Immune System Process Immunoglobulin Transcytosis In Epithelial Cells Humoral Immune Response Mediated By Circulating Immunoglobulin Cellular Defense Response Signal Transduction Fc Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Regulation Of B Cell Receptor Signaling Pathway Fc Receptor-mediated Immune Complex Endocytosis
Pathways
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: FCMR HBP1 HOMEZ LDB3 MAPK6 PML TCAP TP53 TTN YBX1 ZBTB3	3 interacting genes: ANKRD2 HOXD9 ZNHIT3
Entrez ID		26287	9214
HPRD ID		12460	09349
Ensembl ID		ENSG00000165887	ENSG00000162894
Uniprot IDs		A0A0A0MRN9 Q5T457 Q9GZV1	O60667
PDB IDs			7YSG 7YTC 7YTD 7YTE 8BPE 8BPF 8BPG
Enriched GO Terms of Interacting Partners?		Titin-telethonin Complex Sarcomerogenesis Skeletal Muscle Myosin Thick Filament Assembly Myosin Filament Assembly Sarcomere Organization Skeletal Muscle Thin Filament Assembly Detection Of Muscle Stretch Muscle Alpha-actinin Binding Cardiac Myofibril Assembly Muscle Filament Sliding Actomyosin Structure Organization Actin-myosin Filament Sliding Negative Regulation Of Telomere Maintenance Via Telomerase Z Disc Entrainment Of Circadian Clock By Photoperiod Cardiac Muscle Hypertrophy Response To Muscle Stretch I Band Photoperiodism Entrainment Of Circadian Clock Muscle Hypertrophy Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Myofibril Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Skeletal Muscle Contraction Negative Regulation Of Telomere Maintenance Actin-mediated Cell Contraction Cardiac Muscle Cell Development Regulation Of Telomere Maintenance Via Telomerase Structural Constituent Of Muscle Cardiac Muscle Contraction Cardiac Cell Development Detection Of Mechanical Stimulus Somitogenesis DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cellular Senescence Regulation Of Telomere Maintenance Via Telomere Lengthening Response To Gamma Radiation Segmentation Negative Regulation Of Translation In Response To Oxidative Stress Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Heart Development Cardiac Muscle Tissue Morphogenesis High-affinity IgM Receptor Activity Actin Filament-based Movement Cellular Senescence
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