ANKRD2

Gene Name		ankyrin repeat domain 2 (stretch responsive muscle)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Euchromatin Nucleus Cytosol PML Body Sarcomere I Band Intracellular Membrane-bounded Organelle
	Molecular Function	Structural Constituent Of Muscle Titin Binding Protein Kinase B Binding RNA Polymerase II Sequence-specific DNA Binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Muscle Contraction Muscle Organ Development Skeletal Muscle Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Myoblast Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		8 interactors: FAIM3 HBP1 PML TCAP TP53 TTN YBX1 ZBTB3
Entrez ID		26287
HPRD ID		12460
Ensembl ID		ENSG00000165887
Uniprot IDs		Q9GZV1
PDB IDs
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Myosin Thick Filament Assembly Sarcomerogenesis Detection Of Muscle Stretch Myosin Filament Assembly Skeletal Muscle Thin Filament Assembly Skeletal Myofibril Assembly Cardiac Muscle Fiber Development Response To Muscle Stretch Cell Cycle Arrest Adult Heart Development Protein Import Positive Regulation Of Histone Deacetylation Cardiac Myofibril Assembly Entrainment Of Circadian Clock By Photoperiod Positive Regulation Of Protein Deacetylation Cardiac Muscle Hypertrophy Photoperiodism Entrainment Of Circadian Clock Muscle Hypertrophy Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Cellular Senescence Actin-myosin Filament Sliding Muscle Filament Sliding Regulation Of Histone Deacetylation Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Actin-mediated Cell Contraction Negative Regulation Of DNA Replication Detection Of Mechanical Stimulus Regulation Of Protein Deacetylation Muscle Fiber Development Response To Gamma Radiation Cardiac Muscle Contraction Sarcomere Organization DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Cardiac Muscle Tissue Morphogenesis Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Actin Filament-based Movement Muscle Tissue Morphogenesis Regulation Of Tissue Remodeling Heart Contraction Protein Complex Assembly Cell Cycle Process Cardiac Muscle Cell Development Muscle Organ Morphogenesis Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint
Tagcloud ?		a165v a171t actinin2 alternatively cardiomyopathy compaction competition cypher cytoskeletal differs dilated homologue indication lethality lim mechanosensing motif multiprotein myofibrillar myopathy nomenclature pdz sarcomeres spliced striated sumoylation zasp zaspopathy zm