XIAP and CASP9

  • Number of citations of the paper that reports this interaction (PMID 9545235)
  • 169
  • Data Source:
  • HPRD (in vitro, in vivo)

XIAP

CASP9

Gene Name X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase caspase 9, apoptosis-related cysteine peptidase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 67 interactors: ACVRL1 AFP AIFM1 AKT1 AKT2 BIRC5 BRCA1 CASP10 CASP3 CASP7 CASP9 CHEK1 CKS1B COMMD1 DIABLO DTX3 DYNLL2 ELAVL1 ERCC3 GSPT1 HTRA1 HTRA2 IKBKE INPP5D LONRF1 MAGED1 MAP3K2 MAP3K3 MAP3K7 NEK6 NOD1 NOD2 NOTCH1 RAF1 RFC5 RIPK1 RIPK2 RIPK3 RIPK4 SEPT4 SSX2IP STRADB STUB1 TAB1 TAB2 TBK1 TGFBR1 TRAF6 TRIM32 TRIM8 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2I UBE2J2 UBE2N UBE2V1 UBE2V2 UBE2W VPS37C WDYHV1 XAF1 44 interactors: ABL1 AKT1 APAF1 BCL10 BCL2L1 BIRC2 BIRC3 BIRC5 BIRC6 BIRC7 BIRC8 CAPN2 CARD8 CASP10 CASP3 CASP7 CASP8 CYCS DCC DIABLO DSP GMEB1 GZMB HIP1 HSD17B4 HSPD1 ILK JUN LYN MAP2K1 MAP2K2 MAPK1 MAPK3 MSTO1 MZB1 NAIP NLRP1 NOD1 PRKCZ RB1 RNF2 SRF VIM XIAP
Entrez ID 331 842
HPRD ID 02094 03756
Ensembl ID ENSG00000101966 ENSG00000132906
Uniprot IDs B2R9R2 P98170 F8VVS7 P55211
PDB IDs 1C9Q 1F9X 1G3F 1G73 1I3O 1I4O 1I51 1KMC 1NW9 1TFQ 1TFT 2ECG 2JK7 2KNA 2OPY 2OPZ 2POI 2POP 2QRA 2VSL 3CLX 3CM2 3CM7 3EYL 3G76 3HL5 3UW4 3UW5 4EC4 4HY0 4IC2 4IC3 4J3Y 4J44 4J45 4J46 4J47 4J48 1JXQ 1NW9 2AR9 3D9T 3V3K 3YGS
Enriched GO Terms of Interacting Partners?
Tagcloud ?
anthracyclines  antiapoptotic  apaf  bcp  carbinol  childhood  coadministration  cruciferous  cure  doxorubicin  dramatic  evidenced  i3c  iap1  indole  innovative  lymphoblastic  modality  nalm  nontoxic  noxa  opportunities  parp  phytochemical  potentiates  puma  topoisomerase  vegetables  xl 
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp8  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  parp  phenolic  ribose  rosemary  sage  serves  sy5y 
Tagcloud (Difference) ?
anthracyclines  antiapoptotic  apaf  bcp  carbinol  childhood  coadministration  cruciferous  cure  doxorubicin  dramatic  evidenced  i3c  iap1  indole  innovative  lymphoblastic  modality  nalm  nontoxic  noxa  opportunities  phytochemical  potentiates  puma  topoisomerase  vegetables  xl 
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp8  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  phenolic  ribose  rosemary  sage  serves  sy5y 
Tagcloud (Intersection) ?
parp