CLSTN3 and APBA2

Number of citations of the paper that reports this interaction (PubMedID 12972431)
0

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		CLSTN3	APBA2
Description		calsyntenin 3	amyloid beta precursor protein binding family A member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Plasma Membrane Cell Surface Postsynaptic Density Membrane Dendrite Protein-containing Complex Cell Projection Organelle Membrane Contact Site Synapse Postsynaptic Membrane Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse	Cytoplasm Plasma Membrane Dendritic Spine Schaffer Collateral - CA1 Synapse Presynapse
	Molecular Function	Enzyme Inhibitor Activity Calcium Ion Binding Protein Binding Neurexin Family Protein Binding Cell-cell Adhesion Mediator Activity	Amyloid-beta Binding Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Cell Growth Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Synapse Assembly Protein Secretion Negative Regulation Of Lipid Storage L-ascorbic Acid Metabolic Process Synaptic Transmission, Glutamatergic Positive Regulation Of Synaptic Transmission Positive Regulation Of Lipid Catabolic Process Synaptic Transmission, GABAergic Regulation Of Synapse Assembly Positive Regulation Of Synapse Assembly Sympathetic Neuron Projection Extension Cell-cell Adhesion Cold-induced Thermogenesis Lipid Droplet Fusion Negative Regulation Of Lipid Droplet Fusion Positive Regulation Of Protein Localization To Synapse Excitatory Synapse Assembly Inhibitory Synapse Assembly Regulation Of Excitatory Synapse Assembly Negative Regulation Of Excitatory Synapse Assembly Regulation Of Presynapse Assembly Positive Regulation Of Inhibitory Synapse Assembly Adaptive Thermogenesis	In Utero Embryonic Development Chemical Synaptic Transmission Nervous System Development Locomotory Behavior Regulation Of Gene Expression Protein Transport Multicellular Organism Growth Presynaptic Modulation Of Chemical Synaptic Transmission
Pathways			Neurexins and neuroligins
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Schizophrenia ( 30285260)	Longevity (100 years and older) ( 33948810) Response to mTOR inhibitor (rapamycin) ( 24009623) SAPHO syndrome ( 33816493) Skin pigmentation (conditioned on rs1426654 and rs35397) ( 31315583) Temperament ( 22832960)
Interacting Genes		12 interacting genes: APBA2 CMTM7 MAL NKG7 OLFM4 PGAP2 RSPH1 TMEM107 TMEM54 TMEM97 TRAM1L1 ZDHHC22	16 interacting genes: APP ARF3 ARF4 CLSTN1 CLSTN3 HUNK LRP1 LRP2 LRP8 MAGEB6 MAPK6 NECAB3 NRXN1 RELA STXBP1 USP20
Entrez ID		9746	321
HPRD ID		16725	04090
Ensembl ID		ENSG00000139182	ENSG00000034053
Uniprot IDs		Q9BQT9	Q59G28 Q99767
PDB IDs
Enriched GO Terms of Interacting Partners?			Regulation Of Synapse Organization Positive Regulation Of Synaptic Transmission Vesicle-mediated Transport Positive Regulation Of Nervous System Development Glutamatergic Synapse Low-density Lipoprotein Particle Receptor Activity Apolipoprotein Binding Establishment Of Protein Localization Calcium Ion Binding Regulation Of Presynapse Organization Regulation Of Presynapse Assembly Cargo Receptor Activity Regulation Of Nervous System Development Protein Transport Modulation Of Chemical Synaptic Transmission Astrocyte Activation Involved In Immune Response Chemical Synaptic Transmission Intracellular Protein Localization Positive Regulation Of Lysosomal Protein Catabolic Process Positive Regulation Of Developmental Process Golgi Apparatus Trans-synaptic Signaling NMDA Selective Glutamate Receptor Signaling Pathway Synaptic Signaling Regulation Of Synapse Assembly Positive Regulation Of Protein Catabolic Process In The Vacuole Positive Regulation Of Synapse Assembly Receptor Complex Clathrin-coated Pit Endocytosis Retinoid Metabolic Process Regulation Of Lysosomal Protein Catabolic Process Diterpenoid Metabolic Process Positive Regulation Of Multicellular Organismal Process Acetylcholine Receptor Binding Amyloid-beta Binding Terpenoid Metabolic Process Regulation Of Cell Junction Assembly Neuron Projection Morphogenesis Cell Projection Morphogenesis Cellular Response To Growth Factor Stimulus Isoprenoid Metabolic Process Positive Regulation Of Catabolic Process Heparan Sulfate Proteoglycan Binding Astrocyte Activation Positive Regulation Of Cell Junction Assembly Platelet Alpha Granule Transcytosis Regulation Of Amyloid-beta Clearance Cell-cell Signaling
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