CLSTN3 and OLFM4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLSTN3	OLFM4
Description		calsyntenin 3	olfactomedin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Plasma Membrane Cell Surface Postsynaptic Density Membrane Dendrite Protein-containing Complex Cell Projection Organelle Membrane Contact Site Synapse Postsynaptic Membrane Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse	Extracellular Region Extracellular Space Nucleoplasm Mitochondrion Cytosol Plasma Membrane Secretory Granule Protein-containing Complex Specific Granule Lumen Specific Granule Azurophil Granule Intercellular Bridge Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	Enzyme Inhibitor Activity Calcium Ion Binding Protein Binding Neurexin Family Protein Binding Cell-cell Adhesion Mediator Activity	Structural Molecule Activity Protein Binding Cadherin Binding
	Biological Process	Regulation Of Cell Growth Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Synapse Assembly Protein Secretion Negative Regulation Of Lipid Storage L-ascorbic Acid Metabolic Process Synaptic Transmission, Glutamatergic Positive Regulation Of Synaptic Transmission Positive Regulation Of Lipid Catabolic Process Synaptic Transmission, GABAergic Regulation Of Synapse Assembly Positive Regulation Of Synapse Assembly Sympathetic Neuron Projection Extension Cell-cell Adhesion Cold-induced Thermogenesis Lipid Droplet Fusion Negative Regulation Of Lipid Droplet Fusion Positive Regulation Of Protein Localization To Synapse Excitatory Synapse Assembly Inhibitory Synapse Assembly Regulation Of Excitatory Synapse Assembly Negative Regulation Of Excitatory Synapse Assembly Regulation Of Presynapse Assembly Positive Regulation Of Inhibitory Synapse Assembly Adaptive Thermogenesis	Immune Response Cell Adhesion Signal Transduction Negative Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Immune Response Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Schizophrenia ( 30285260)	Adult body size ( 32376654) Adventurousness ( 30643258) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 29381148 24861553 25673413 25953783 28448500 26961502) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body size at age 10 ( 32376654) Cerebrospinal P-tau181p levels ( 28247064) Childhood body mass index ( 26604143) Depression ( 29700475) Hip circumference ( 25673412) Immune response to anthrax vaccine ( 22658931) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 27479909) Multisite chronic pain ( 33830993) Obesity ( 23563607 22484627) Obesity-related traits ( 23251661) Waist circumference ( 25673412)
Interacting Genes		12 interacting genes: APBA2 CMTM7 MAL NKG7 OLFM4 PGAP2 RSPH1 TMEM107 TMEM54 TMEM97 TRAM1L1 ZDHHC22	36 interacting genes: APP AQP2 AQP3 BSCL2 C3 CFTR CLDN7 CLEC17A CLEC7A CLSTN3 CLTRN CREB3L1 EREG FAM209A FNDC9 IL11RA ITM2C KASH5 KIR2DL3 KIR3DL3 LDLRAD1 LEUTX LHFPL2 PVR PVRIG QPCTL SAR1A SLC18A1 SLC22A23 SUSD3 SYNE4 TFR2 TMEM130 TNFSF11 TNFSF14 TSPAN18
Entrez ID		9746	10562
HPRD ID		16725	06580
Ensembl ID		ENSG00000139182	ENSG00000102837
Uniprot IDs		Q9BQT9	Q6UX06
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Plasma Membrane Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Receptor Ligand Activity Multicellular Organismal-level Chemical Homeostasis Water Transport Multicellular Organismal-level Water Homeostasis Fluid Transport Glycerol Transmembrane Transport Multicellular Organismal-level Homeostasis Renal Water Transport Polyol Transmembrane Transport Meiotic Nuclear Membrane Microtubule Tethering Complex Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Yeast Cell Maturation Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Endocytosis Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Neuron Remodeling Water Channel Activity Organic Hydroxy Compound Transport Positive Regulation Of Defense Response Cell Surface Regulation Of Immune System Process Renal Water Homeostasis
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