NID1 and FBLN2

Number of citations of the paper that reports this interaction (PMID 7500359)
18

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		NID1	FBLN2
Gene Name		nidogen 1	fibulin 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Basal Lamina Extracellular Matrix Extracellular Vesicular Exosome Cell Periphery	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Matrix Vesicle Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Collagen Binding Laminin Binding Laminin-1 Binding Proteoglycan Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Extracellular Matrix Binding
	Biological Process	Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Glomerular Basement Membrane Development Basement Membrane Organization	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways		Laminin interactions Degradation of the extracellular matrix	Molecules associated with elastic fibres Elastic fibre formation
Drugs
Diseases
GWAS		Cutaneous nevi ( 21478494)	Bipolar disorder (mood-incongruent) ( 23092984)
Protein-Protein Interactions		21 interactors: APP COL13A1 COL1A1 COL4A1 FBLN1 FBLN2 FGA FGB HSPG2 ITGAV ITGB3 LACRT LAMA1 LAMC1 LAMC2 LGALS3BP PLAU PLXDC1 PRELP PTPRF SKIL	22 interactors: ACAN ATN1 BCAN COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 ELN FBN1 FN1 HSPG2 ITGB3 LAMA1 LAMA5 LAMC2 NID1 PRELP VCAN ZNF408
Entrez ID		4811	2199
HPRD ID		00574	00630
Ensembl ID		ENSG00000116962	ENSG00000163520
Uniprot IDs		P14543	F5H1F3 P98095 Q86V58 Q9Y3V7
PDB IDs		1NDX
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Disassembly Cell Adhesion Regulation Of Body Fluid Levels Cell-substrate Adhesion Blood Coagulation Hemostasis Blood Vessel Development Vasculature Development Cell-matrix Adhesion Platelet Degranulation Locomotion Wound Healing Chemotaxis Platelet Activation Regulation Of Cell-substrate Adhesion Regulation Of Cell Adhesion Axon Guidance Blood Vessel Morphogenesis Response To Wounding Anatomical Structure Morphogenesis Movement Of Cell Or Subcellular Component Negative Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Axonogenesis Platelet Aggregation Cardiovascular System Development Tissue Development Retinal Blood Vessel Morphogenesis Endochondral Ossification Axon Development Substrate Adhesion-dependent Cell Spreading Angiogenesis Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Receptor Biosynthetic Process Apolipoprotein A-I-mediated Signaling Pathway Response To External Stimulus Positive Regulation Of Cell Morphogenesis Involved In Differentiation Cell-substrate Junction Assembly Neuron Projection Morphogenesis Vesicle-mediated Transport Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Anatomical Structure Formation Involved In Morphogenesis Developmental Process Collagen Catabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Morphogenesis Involved In Differentiation Negative Regulation Of Lipoprotein Metabolic Process Multicellular Organismal Development	Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Anatomical Structure Development System Development Developmental Process Multicellular Organismal Development Cell Adhesion Cell Morphogenesis Involved In Differentiation Glycosaminoglycan Catabolic Process Cardiovascular System Development Blood Vessel Morphogenesis Locomotion Catabolic Process Blood Vessel Development Cell Morphogenesis Nervous System Development Angiogenesis Vasculature Development Movement Of Cell Or Subcellular Component Anatomical Structure Morphogenesis Glycosaminoglycan Biosynthetic Process Axon Guidance Tissue Development Cell-substrate Junction Assembly Cell Development Organ Development Axonogenesis Glomerular Basement Membrane Development Renal System Development Cell Projection Morphogenesis Glycosaminoglycan Metabolic Process Axon Development Cell Part Morphogenesis Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Urogenital System Development Pathogenesis Neuron Projection Morphogenesis Cell Differentiation Proteoglycan Metabolic Process Cell Projection Organization Neuron Projection Development Retinal Blood Vessel Morphogenesis Kidney Development Neurogenesis
Tagcloud ?		accordance biogenesis bound brains clip details enriched immunoprecipitation intron linking messenger mirna mirnas neurexin neurodegeneration neurodevelopmental neurological nrxn1 pirnas processed reexamine represses rnas seq srnas systematically tar tardbp tdp	3p 3p24 anonymous arrayed candidate chromosomal closely colocation d3s1585 excluded fibulin generated intragenic linkage locus lod map marfan marker markers matrix mfs2 p25 placed point polymorphic polymorphisms scores sequencing
Tagcloud (Difference) ?		accordance biogenesis bound brains clip details enriched immunoprecipitation intron linking messenger mirna mirnas neurexin neurodegeneration neurodevelopmental neurological nrxn1 pirnas processed reexamine represses rnas seq srnas systematically tar tardbp tdp	3p 3p24 anonymous arrayed candidate chromosomal closely colocation d3s1585 excluded fibulin generated intragenic linkage locus lod map marfan marker markers matrix mfs2 p25 placed point polymorphic polymorphisms scores sequencing
Tagcloud (Intersection) ?