APBB1IP

Gene Name		amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
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Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Lamellipodium
	Molecular Function	Protein Binding
	Biological Process	Signal Transduction Blood Coagulation Platelet Activation
Pathways		p130Cas linkage to MAPK signaling for integrins Integrin alphaIIb beta3 signaling GRB2:SOS provides linkage to MAPK signaling for Integrins Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation)
Drugs
Diseases
GWAS		Inflammatory biomarkers ( 22228203) Response to angiotensin II receptor blocker therapy ( 22566498)
Protein-protein Interactions		8 interactors: EVL GAS7 NDN PFN1 PRPF40A RAP1A VASP ZDHHC17
Entrez ID		54518
HPRD ID		16420
Ensembl ID		ENSG00000077420
Uniprot IDs		B4E100 Q7Z5R6
PDB IDs		3ZDL
Enriched GO Terms of Interacting Partners?		Actin Polymerization Or Depolymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Regulation Of Cellular Component Organization Cytoskeleton Organization Regulation Of Ruffle Assembly Nervous System Development Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Actin Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Cytoskeleton Organization Neuron Projection Morphogenesis Actin Filament-based Process Generation Of Neurons Neurogenesis Neuron Projection Development Cell Projection Morphogenesis Positive Regulation Of Stress Fiber Assembly Actin Filament Organization Cell Part Morphogenesis Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Cellular Component Biogenesis Cell Development Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Neuron Development Regulation Of Actin Cytoskeleton Organization Regulation Of Stress Fiber Assembly Protein Homotetramerization Cell Morphogenesis Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Neuron Differentiation Cell Projection Organization Regulation Of Cell Projection Organization Locomotion Anatomical Structure Morphogenesis Regulation Of Cytoskeleton Organization Protein Tetramerization Neural Tube Closure Axonogenesis System Development Regulation Of Cell Projection Assembly Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Neural Tube Formation Response To Growth Factor
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