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NCF4 and CORO1A
Number of citations of the paper that reports this interaction (PMID
9365277
)
27
Data Source:
HPRD
(in vitro)
NCF4
CORO1A
Gene Name
neutrophil cytosolic factor 4, 40kDa
coronin, actin binding protein, 1A
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Endosome Membrane
Membrane
Phagolysosome
NADPH Oxidase Complex
Immunological Synapse
Phagocytic Cup
Nucleus
Cytoplasm
Early Endosome
Actin Filament
Plasma Membrane
Cell-cell Junction
Membrane
Lamellipodium
Axon
Phagocytic Vesicle Membrane
Cortical Actin Cytoskeleton
Protein Complex
Phagocytic Vesicle
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Superoxide-generating NADPH Oxidase Activator Activity
Phosphatidylinositol-3-phosphate Binding
Protein Dimerization Activity
Protein Binding
Protein C-terminus Binding
Cytoskeletal Protein Binding
Protein Homodimerization Activity
Phosphatidylinositol 3-kinase Binding
Poly(A) RNA Binding
Actin Filament Binding
Biological Process
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Positive Regulation Of Catalytic Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Interaction With Host
Oxidation-reduction Process
Phagosome Maturation
Phagolysosome Assembly
Calcium Ion Transport
Phagocytosis
Movement Of Cell Or Subcellular Component
Actin Filament Organization
Regulation Of Cell Shape
Actin Cytoskeleton Organization
Positive Regulation Of Cell Migration
Leukocyte Chemotaxis
Regulation Of Actin Filament Polymerization
Negative Regulation Of Vesicle Fusion
Cell-substrate Adhesion
Uropod Organization
Nerve Growth Factor Signaling Pathway
Positive Regulation Of T Cell Proliferation
T Cell Homeostasis
Negative Regulation Of Neuron Apoptotic Process
Innate Immune Response
Homeostasis Of Number Of Cells Within A Tissue
Positive Chemotaxis
Negative Regulation Of Actin Nucleation
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Early Endosome To Recycling Endosome Transport
Cellular Response To Interleukin-4
Pathways
Signaling by VEGF
Phagosomal maturation (early endosomal stage)
Latent infection of Homo sapiens with Mycobacterium tuberculosis
Class I MHC mediated antigen processing & presentation
Antigen processing-Cross presentation
VEGFA-VEGFR2 Pathway
Cross-presentation of particulate exogenous antigens (phagosomes)
Adaptive Immune System
Drugs
Diseases
GWAS
Atopic dermatitis (
22197932
)
Protein-Protein Interactions
10 interactors:
CORO1A
CYBA
CYBB
MSN
NCF1
NCF2
PRKCD
PRKDC
TXN
XRCC6
17 interactors:
ACTB
FHL3
FSD2
GIT2
GOLGA2
LMO2
MAGOH
NCF4
POLR1C
POT1
SMAD3
SMARCD1
SPATA20
STAT3
TAB1
THBS1
YTHDC1
Entrez ID
4689
11151
HPRD ID
03289
05414
Ensembl ID
ENSG00000100365
ENSG00000102879
Uniprot IDs
Q15080
P31146
PDB IDs
1H6H
1OEY
1W6X
1W70
1Z9Q
2DYB
Enriched GO Terms of Interacting Partners
?
Innate Immune Response
Phagosome Maturation
Respiratory Burst
Superoxide Anion Generation
Immune Response
Immune System Process
Defense Response
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Superoxide Metabolic Process
Hydrogen Peroxide Biosynthetic Process
Interaction With Host
Reactive Oxygen Species Metabolic Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Response To Stress
Hydrogen Peroxide Metabolic Process
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Peptide Antigen
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Antigen Processing And Presentation
Enzyme Linked Receptor Protein Signaling Pathway
Response To Radiation
Response To Ionizing Radiation
Response To External Stimulus
Double-strand Break Repair Via Nonhomologous End Joining
Response To Abiotic Stimulus
Organelle Organization
V(D)J Recombination
Cellular Response To Stimulus
Regulation Of Ion Transport
Positive Regulation Of Blood Pressure
Homeostatic Process
Signal Transduction
Response To Gamma Radiation
Regulation Of Cell Death
Cellular Defense Response
Cellular Response To Ionizing Radiation
Signaling
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Cell Communication
Positive Regulation Of Phospholipid Scramblase Activity
Smooth Muscle Hypertrophy
Positive Regulation Of Glucosylceramide Catabolic Process
Positive Regulation Of Sphingomyelin Catabolic Process
Negative Regulation Of Glomerular Filtration By Angiotensin
Telomere Maintenance
Regulation Of Calcium Ion Transport Into Cytosol
Response To Stimulus
Positive Regulation Of Type I Interferon Production
Cellular Response To Organic Substance
Positive Regulation Of Transforming Growth Factor Beta Production
Behavioral Response To Pain
Positive Regulation Of Metabolic Process
Immune Response
Enzyme Linked Receptor Protein Signaling Pathway
Immune System Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Catalytic Activity
Response To Pain
Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Focal Adhesion Assembly
Heart Morphogenesis
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Regulation Of Cell Junction Assembly
Negative Regulation Of CGMP-mediated Signaling
Positive Regulation Of Transforming Growth Factor Beta3 Production
Negative Regulation Of Dendritic Cell Antigen Processing And Presentation
Positive Regulation Of DNA Strand Elongation
Positive Regulation Of Cellular Metabolic Process
DNA-templated Transcription, Termination
Regulation Of Immune System Process
Multicellular Organismal Development
Defense Response
Positive Regulation Of Cytokine Production
Multicellular Organismal Response To Stress
Organ Development
Engulfment Of Apoptotic Cell
Negative Regulation Of Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Telomere Formation Via Telomerase
Evasion Or Tolerance Of Host Defenses By Virus
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Interaction With Host
Transcription From RNA Polymerase II Promoter
Regulation Of Metabolic Process
Positive Regulation Of Chemotaxis
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Positive Regulation Of Gene Expression
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Positive Regulation Of Extracellular Matrix Assembly
Negative Regulation Of Nitric Oxide Mediated Signal Transduction
Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport
Negative Regulation Of Endothelial Cell Chemotaxis
Positive Regulation Of Cell-substrate Adhesion
Regulation Of Cell-matrix Adhesion
System Development
Positive Regulation Of Behavior
Regulation Of Catalytic Activity
Tagcloud
?
anion
besides
biopsies
chl
copy
cyba
cybb
deleterious
deletions
downregulation
exert
hodgkin
hybridisation
lines
lymphoma
nadph
ncf1
ncf2
oxidase
phagocytic
profiling
progenitors
proved
quantify
recurrent
reed
sternberg
subsets
superoxide
Tagcloud (Difference)
?
anion
besides
biopsies
chl
copy
cyba
cybb
deleterious
deletions
downregulation
exert
hodgkin
hybridisation
lines
lymphoma
nadph
ncf1
ncf2
oxidase
phagocytic
profiling
progenitors
proved
quantify
recurrent
reed
sternberg
subsets
superoxide
Tagcloud (Intersection)
?