NCF4 and MSN

Number of citations of the paper that reports this interaction (PMID 11716484)
20

Data Source:
HPRD (in vivo, in vitro)

		NCF4	MSN
Gene Name		neutrophil cytosolic factor 4, 40kDa	moesin
Image
Gene Ontology Annotations	Cellular Component	Cytosol Endosome Membrane Membrane Phagolysosome NADPH Oxidase Complex	Uropod Extracellular Space Cytoplasm Cytoskeleton Plasma Membrane Microvillus Focal Adhesion Basolateral Plasma Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Filopodium Microvillus Membrane Vesicle Apical Part Of Cell Extracellular Vesicular Exosome Cell Periphery Blood Microparticle
	Molecular Function	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity Phosphatidylinositol-3-phosphate Binding Protein Dimerization Activity	Double-stranded RNA Binding Actin Binding Receptor Binding Structural Constituent Of Cytoskeleton Protein Binding Protein Kinase Binding Cell Adhesion Molecule Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Immune Response Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Positive Regulation Of Catalytic Activity Vascular Endothelial Growth Factor Receptor Signaling Pathway Interaction With Host Oxidation-reduction Process Phagosome Maturation	Movement Of Cell Or Subcellular Component Leukocyte Cell-cell Adhesion Positive Regulation Of Gene Expression Membrane To Membrane Docking Leukocyte Migration Establishment Of Endothelial Barrier Regulation Of Lymphocyte Migration
Pathways		Signaling by VEGF Phagosomal maturation (early endosomal stage) Latent infection of Homo sapiens with Mycobacterium tuberculosis Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation VEGFA-VEGFR2 Pathway Cross-presentation of particulate exogenous antigens (phagosomes) Adaptive Immune System	Axon guidance L1CAM interactions Recycling pathway of L1
Drugs
Diseases
GWAS		Atopic dermatitis ( 22197932)
Protein-Protein Interactions		10 interactors: CORO1A CYBA CYBB MSN NCF1 NCF2 PRKCD PRKDC TXN XRCC6	24 interactors: BCAP31 CD44 CD46 CD93 CDK11B EZR ICAM1 ICAM2 ICAM3 L1CAM NCF1 NCF4 PLEC PPM1A PPM1B PRKCQ ROCK1 SELL SELPLG SLC9A3R1 SPN TERF1 TSC1 VCAM1
Entrez ID		4689	4478
HPRD ID		03289	02399
Ensembl ID		ENSG00000100365	ENSG00000147065
Uniprot IDs		Q15080	P26038
PDB IDs		1H6H 1OEY 1W6X 1W70 1Z9Q 2DYB	1E5W 1EF1 1SGH
Enriched GO Terms of Interacting Partners?		Innate Immune Response Phagosome Maturation Respiratory Burst Superoxide Anion Generation Immune Response Immune System Process Defense Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Superoxide Metabolic Process Hydrogen Peroxide Biosynthetic Process Interaction With Host Reactive Oxygen Species Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Response To Stress Hydrogen Peroxide Metabolic Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Peptide Antigen Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Antigen Processing And Presentation Enzyme Linked Receptor Protein Signaling Pathway Response To Radiation Response To Ionizing Radiation Response To External Stimulus Double-strand Break Repair Via Nonhomologous End Joining Response To Abiotic Stimulus Organelle Organization V(D)J Recombination Cellular Response To Stimulus Regulation Of Ion Transport Positive Regulation Of Blood Pressure Homeostatic Process Signal Transduction Response To Gamma Radiation Regulation Of Cell Death Cellular Defense Response Cellular Response To Ionizing Radiation Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cell Communication Positive Regulation Of Phospholipid Scramblase Activity Smooth Muscle Hypertrophy Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Negative Regulation Of Glomerular Filtration By Angiotensin Telomere Maintenance Regulation Of Calcium Ion Transport Into Cytosol Response To Stimulus Positive Regulation Of Type I Interferon Production Cellular Response To Organic Substance	Membrane To Membrane Docking Single Organismal Cell-cell Adhesion Cell Adhesion Leukocyte Migration Leukocyte Cell-cell Adhesion Leukocyte Tethering Or Rolling Positive Regulation Of Cell Adhesion Immune System Process Regulation Of Cell Adhesion Positive Regulation Of T Cell Proliferation Cellular Extravasation Membrane Docking Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Immune Response Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Cell-cell Adhesion Locomotion Regulation Of Immune System Process Regulation Of T Cell Proliferation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Movement Of Cell Or Subcellular Component Execution Phase Of Apoptosis Cell Migration Regulation Of Cell-cell Adhesion Cell Motility Positive Regulation Of T Cell Activation Cell Surface Receptor Signaling Pathway Immune Response Apoptotic Process Blood Coagulation Inflammatory Response Hemostasis Cell Activation Programmed Cell Death Cell Death Death Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Negative Regulation Of Signal Transduction Leukocyte Activation Interferon-gamma-mediated Signaling Pathway Response To Stimulus Regulation Of T Cell Activation Innate Immune Response Positive Regulation Of Cell Activation Negative Regulation Of Signaling Cellular Response To Interferon-gamma Regulation Of Body Fluid Levels
Tagcloud ?		anion besides biopsies chl copy cyba cybb deleterious deletions downregulation exert hodgkin hybridisation lines lymphoma nadph ncf1 ncf2 oxidase phagocytic profiling progenitors proved quantify recurrent reed sternberg subsets superoxide	assignments cen discordancy est00675 est00745 est00795 est00887 est00896 est01041 est01471 est01583 est01627 est01650 est01678 est01744 ests globule l18a l1a l1b moesin multiplexed s14 subregionally sulfurtransferase thiosulfate transhydrogenase xp11 xpter
Tagcloud (Difference) ?		anion besides biopsies chl copy cyba cybb deleterious deletions downregulation exert hodgkin hybridisation lines lymphoma nadph ncf1 ncf2 oxidase phagocytic profiling progenitors proved quantify recurrent reed sternberg subsets superoxide	assignments cen discordancy est00675 est00745 est00795 est00887 est00896 est01041 est01471 est01583 est01627 est01650 est01678 est01744 ests globule l18a l1a l1b moesin multiplexed s14 subregionally sulfurtransferase thiosulfate transhydrogenase xp11 xpter
Tagcloud (Intersection) ?