MYL1 and EPB41

Number of citations of the paper that reports this interaction (PMID 11071908)
5

Data Source:
HPRD (in vitro)

		MYL1	EPB41
Gene Name		myosin, light chain 1, alkali; skeletal, fast	erythrocyte membrane protein band 4.1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Muscle Myosin Complex Myofibril Sarcomere	Nucleus Golgi Apparatus Plasma Membrane Spectrin Spectrin-associated Cytoskeleton Extrinsic Component Of Membrane Cortical Cytoskeleton Intracellular Membrane-bounded Organelle Protein Complex
	Molecular Function	Calcium Ion Binding Structural Constituent Of Muscle	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Spectrin Binding
	Biological Process	Muscle Contraction Muscle Filament Sliding Cardiac Muscle Contraction	Blood Circulation Actin Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Positive Regulation Of Protein Binding
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ACTA1 ACTA2 APP EPB41	39 interactors: ACTA1 APP BCAM C2CD2L CASK CD44 CENPJ CLNS1A CRYAB DLG1 DRD2 DRD3 EGFR EIF3G EPB42 FKBP2 GDI1 GYPC KPNA2 MACROD1 MYL1 NPPA NUMA1 PRKCB RWDD2B SEC14L1 SLC4A1 SMAD3 SPTAN1 SPTB SPTBN1 TJP2 TPM1 TUBA4A U2AF1 U2AF2 YWHAB YWHAQ ZCCHC10
Entrez ID		4632	2035
HPRD ID		01180	00558
Ensembl ID		ENSG00000168530	ENSG00000159023
Uniprot IDs		P05976	E9PEW9 P11171 Q1WWM3 Q29RX4 Q59F12
PDB IDs			1GG3 2RQ1 3QIJ
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Cell Growth Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Muscle Contraction Regulation Of Binding Muscle System Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Glomerular Mesangial Cell Development Blood Circulation Axon Choice Point Recognition Skeletal Muscle Thin Filament Assembly Mesangial Cell Development Renal Interstitial Fibroblast Development Skeletal Myofibril Assembly Neuron Remodeling Skeletal Muscle Adaptation Cell Development Response To External Stimulus Vascular Smooth Muscle Contraction Growth Cellular Copper Ion Homeostasis Glomerulus Vasculature Development Copper Ion Homeostasis Suckling Behavior Actin Cytoskeleton Organization Skeletal Muscle Fiber Development Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Cortical Actin Cytoskeleton Organization Actin Filament-based Process Cortical Cytoskeleton Organization Myotube Cell Development Neuron Maturation MRNA Polyadenylation Response To Lithium Ion Regulation Of Epidermal Growth Factor-activated Receptor Activity Vasoconstriction Actin-myosin Filament Sliding Muscle Filament Sliding Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Cell Differentiation Involved In Kidney Development Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Organ Development Actin-mediated Cell Contraction	Regulation Of Cellular Component Organization Positive Regulation Of Transport Muscle System Process Cell Development Regulation Of Establishment Of Protein Localization Regulation Of Organelle Organization Muscle Contraction Axonogenesis Movement Of Cell Or Subcellular Component Axon Guidance Axon Development System Development Regulation Of Protein Localization Cellular Component Assembly Regulation Of Cellular Localization Cell Morphogenesis Involved In Neuron Differentiation Cell Differentiation Neuron Projection Morphogenesis Anatomical Structure Development Anatomical Structure Morphogenesis Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Dopamine Receptor Signaling Pathway Regulation Of Cytoskeleton Organization Response To External Stimulus Cell Morphogenesis Involved In Differentiation Apoptotic Process Regulation Of Systemic Arterial Blood Pressure Regulation Of Actin Cytoskeleton Organization Programmed Cell Death Multicellular Organismal Development Muscle Filament Sliding Actin-myosin Filament Sliding Ion Homeostasis Negative Regulation Of Protein Kinase B Signaling Cell Death Death Cell Morphogenesis Neuron Projection Development Negative Regulation Of Transport Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Chemotaxis Cell Projection Morphogenesis Regulation Of Dopamine Receptor Signaling Pathway Developmental Process Regulation Of Protein Kinase B Signaling Regulation Of Protein Transport Cell Part Morphogenesis Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Cell Projection Organization
Tagcloud ?		acz advantages alleles beyond cassette ce cre disadvantages embryogenesis extends foreseeable immediate inducible knock knocked myf6 myod1 myog myogenic pax3 questions r26r rendering replacing reporter resource skeletal tamoxifen tightly	ank1 antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1
Tagcloud (Difference) ?		acz advantages alleles beyond cassette ce cre disadvantages embryogenesis extends foreseeable immediate inducible knock knocked myf6 myod1 myog myogenic pax3 questions r26r rendering replacing reporter resource skeletal tamoxifen tightly	ank1 antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1
Tagcloud (Intersection) ?