MYL1 and ACTA2

Number of citations of the paper that reports this interaction (PMID 11707283)
2

Data Source:
HPRD (in vitro)

		MYL1	ACTA2
Gene Name		myosin, light chain 1, alkali; skeletal, fast	actin, alpha 2, smooth muscle, aorta
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Muscle Myosin Complex Myofibril Sarcomere	Extracellular Space Cytoplasm Cytosol Actin Cytoskeleton Smooth Muscle Contractile Fiber Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Structural Constituent Of Muscle	ATP Binding Protein Kinase Binding
	Biological Process	Muscle Contraction Muscle Filament Sliding Cardiac Muscle Contraction	Muscle Contraction Regulation Of Blood Pressure Response To Virus Vascular Smooth Muscle Contraction Glomerular Mesangial Cell Development
Pathways		Striated Muscle Contraction	Smooth Muscle Contraction
Drugs
Diseases
GWAS			Immunoglobulin A ( 20694011)
Protein-Protein Interactions		4 interactors: ACTA1 ACTA2 APP EPB41	16 interactors: CCT4 CCT5 CFL1 CREBBP DNASE1 EP300 GC MINK1 MYL1 MYOC PCYT1B PRKCD SHBG SNTA1 TMSB4X YBX1
Entrez ID		4632	59
HPRD ID		01180	00031
Ensembl ID		ENSG00000168530	ENSG00000107796
Uniprot IDs		P05976	D2JYH4 P62736
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Cell Growth Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Muscle Contraction Regulation Of Binding Muscle System Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Glomerular Mesangial Cell Development Blood Circulation Axon Choice Point Recognition Skeletal Muscle Thin Filament Assembly Mesangial Cell Development Renal Interstitial Fibroblast Development Skeletal Myofibril Assembly Neuron Remodeling Skeletal Muscle Adaptation Cell Development Response To External Stimulus Vascular Smooth Muscle Contraction Growth Cellular Copper Ion Homeostasis Glomerulus Vasculature Development Copper Ion Homeostasis Suckling Behavior Actin Cytoskeleton Organization Skeletal Muscle Fiber Development Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Cortical Actin Cytoskeleton Organization Actin Filament-based Process Cortical Cytoskeleton Organization Myotube Cell Development Neuron Maturation MRNA Polyadenylation Response To Lithium Ion Regulation Of Epidermal Growth Factor-activated Receptor Activity Vasoconstriction Actin-myosin Filament Sliding Muscle Filament Sliding Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Cell Differentiation Involved In Kidney Development Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Organ Development Actin-mediated Cell Contraction	N-terminal Peptidyl-lysine Acetylation Regulation Of Actin Filament-based Process N-terminal Protein Amino Acid Acetylation Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Protein Dephosphorylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Blood Coagulation N-terminal Protein Amino Acid Modification Hemostasis Negative Regulation Of Cytoskeleton Organization Regulation Of Cellular Response To Heat Platelet Activation Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Toxin Transport Binding Of Sperm To Zona Pellucida Positive Regulation Of Dephosphorylation Regulation Of Body Fluid Levels Sperm-egg Recognition Wound Healing Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of MAPK Cascade Regulation Of DNA-templated Transcription In Response To Stress Muscle System Process 'de Novo' Posttranslational Protein Folding Actin Filament-based Process Histone H2B Acetylation Positive Regulation Of Phospholipid Scramblase Activity Skeletal Muscle Hypertrophy Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process ERBB2-ERBB3 Signaling Pathway Regulation Of Vasoconstriction By Circulating Norepinephrine Primary Spermatocyte Growth 'de Novo' Protein Folding Developmental Process Cellular Response To Heat Cell Activation Cell-cell Recognition Termination Of Signal Transduction Response To Wounding Rhythmic Process Platelet Degranulation Negative Regulation Of Actin Filament Polymerization Regulation Of Cellular Component Size Positive Regulation Of Type I Interferon Production Positive Regulation Of Phospholipid Catabolic Process Glucosylceramide Catabolic Process ERBB2 Signaling Pathway
Tagcloud ?		acz advantages alleles beyond cassette ce cre disadvantages embryogenesis extends foreseeable immediate inducible knock knocked myf6 myod1 myog myogenic pax3 questions r26r rendering replacing reporter resource skeletal tamoxifen tightly	attaining buffalo calves cirbp cryopreservation cryopreserved cyp11a1 d20s20 dairies dimethylsulfoxide dismutase2 dmso fbs fcc freezing germplasm homeobox leydig maturity pou pou5f1 protein3 rbm3 sod2 subfamily surviving testicular uncontrolled vim
Tagcloud (Difference) ?		acz advantages alleles beyond cassette ce cre disadvantages embryogenesis extends foreseeable immediate inducible knock knocked myf6 myod1 myog myogenic pax3 questions r26r rendering replacing reporter resource skeletal tamoxifen tightly	attaining buffalo calves cirbp cryopreservation cryopreserved cyp11a1 d20s20 dairies dimethylsulfoxide dismutase2 dmso fbs fcc freezing germplasm homeobox leydig maturity pou pou5f1 protein3 rbm3 sod2 subfamily surviving testicular uncontrolled vim
Tagcloud (Intersection) ?