MYBPC2 and MYOM2

Number of citations: 48 (PubMedID 23414517)
Data Source: BioGRID (two hybrid)

		MYBPC2	MYOM2
Name		myosin binding protein C2	myomesin 2
Structure			No pdb structure
GO Annotations	Cellular Component	Cytosol M Band Myosin Filament	Cytoplasm Mitochondrion M Band Myosin Filament
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle	Structural Molecule Activity Protein Binding Structural Constituent Of Muscle Kinase Binding
	Biological Process	Cell Adhesion Sarcomere Organization	Extraocular Skeletal Muscle Development Muscle Contraction Sarcomere Organization
Pathways		Striated Muscle Contraction	None
GWAS		Primary biliary cholangitis ( 26394269 )	Ankylosing spondylitis ( 30946743 ) Diisocyanate-induced asthma ( 25918132 ) Heel bone mineral density x serum urate levels interaction ( 34046847 ) Heschl's gyrus morphology ( 25130324 ) Metabolite levels ( 23823483 ) Opioid use cessation ( 31936517 ) Toenail selenium levels ( 25343990 )
Interacting Genes		31 interacting genes: ACTN2 AMOT AOC3 CCT6A CMYA5 COL12A1 DST DYSF FLNB FLNC FSD2 GABARAP GAS7 HSPA1B ITGB5 MAD2L2 MSN MYBPC1 MYBPH MYH8 MYOM2 NF2 PCDH12 PDE4DIP RANBP2 SDCBP SGCG TRIM63 TRIP11 TTN TULP3	14 interacting genes: ANKRD1 CKM DYSF HSPB2 JMJD1C MYBPC2 MYH7 MYH9 NEB RPS6 SEC31A TAF1 TNNT1 TTN
Entrez ID		4606	9172
HPRD ID		01184	04619
Ensembl ID		ENSG00000086967	ENSG00000036448
Uniprot IDs		A0A140VJQ0 Q14324	P54296
PDB IDs		2E7C 2EDK 2EDN	Not available
GO Terms Enriched among Interactors		Actin Filament-based Process M Band Actin Cytoskeleton Organization Cytoskeleton Organization Sarcomere Organization Structural Constituent Of Muscle Actomyosin Structure Organization Myosin Filament Z Disc Cytoskeletal Protein Binding Organelle Organization Actin Binding Cytoskeleton Focal Adhesion Titin Binding Positive Regulation Of Organelle Organization Cytoplasm Positive Regulation Of Supramolecular Fiber Organization Cell Adhesion Positive Regulation Of Cytoskeleton Organization Actin Filament Binding Myofibril Positive Regulation Of Microtubule Nucleation Positive Regulation Of Early Endosome To Late Endosome Transport Actin Cytoskeleton Integrin Binding Positive Regulation Of Protein Localization To Early Endosome Regulation Of Organelle Organization Positive Regulation Of Protein Localization To Endosome Positive Regulation Of Cellular Component Biogenesis Muscle Filament Sliding Phosphatidylinositol-4,5-bisphosphate Binding Filopodium Pseudopodium Actin-myosin Filament Sliding Regulation Of Early Endosome To Late Endosome Transport Muscle Contraction Stress Fiber Regulation Of Microtubule Nucleation Regulation Of Supramolecular Fiber Organization Extracellular Exosome Calcium Ion Binding Positive Regulation Of Cellular Component Organization Plasma Membrane Enzyme Binding Muscle Cell Development Sarcolemma Muscle System Process Regulation Of Organelle Assembly Regulation Of Intracellular Transport	Sarcomere Organization Actomyosin Structure Organization Actin Filament-based Process Myosin Filament Somatic Muscle Development Actin-mediated Cell Contraction Skeletal Muscle Contraction Actin Cytoskeleton Organization Structural Constituent Of Muscle Myofibril Transition Between Fast And Slow Fiber Cardiac Muscle Tissue Morphogenesis Actin Filament-based Movement Actin Filament Binding Muscle Tissue Morphogenesis Supramolecular Fiber Regulation Of Skeletal Muscle Adaptation Striated Muscle Contraction Muscle Filament Sliding Actin-myosin Filament Sliding Actin Binding M Band Cardiac Muscle Hypertrophy Z Disc Myosin II Complex Response To Muscle Stretch I Band Muscle Hypertrophy Microfilament Motor Activity Calmodulin Binding Muscle Contraction Cardiac Muscle Contraction Cytoskeleton Organization Myosin Complex Cytoskeletal Motor Activity Cortical Granule Exocytosis Positive Regulation Of Androgen Receptor Signaling Pathway Slow-twitch Skeletal Muscle Fiber Contraction Monocyte Activation Involved In Immune Response Sarcomere Muscle System Process Regulation Of The Force Of Skeletal Muscle Contraction Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Uropod Organization Actin Cytoskeleton Negative Regulation Of Actin Filament Severing Positive Regulation Of Protein Processing In Phagocytic Vesicle Negative Regulation Of Protein Autoubiquitination P53 Binding Titin-telethonin Complex